Protein Variants | Comment | Organism |
---|---|---|
E264K | single nucleotide variant, identified within a South African mixed ancestry population, substitution occupies less conformational clusters of folded states as compared to the wild-type and is destabilizing | Homo sapiens |
E264K | single nucleotide variant, identified within a South African mixed ancestry population. Less thermodynamically stable protein structure is predicted | Homo sapiens |
N245I | single nucleotide variant, identified within a South African mixed ancestry population. Thermodynamically stabilizing effect structure is predicted and affecting NAT1 protein function | Homo sapiens |
R242M | single nucleotide variant, identified within a South African mixed ancestry population, displays a similar profile to the published variant, I263V (proposed fast acetylator), and the wild-type protein structure | Homo sapiens |
V231G | single nucleotide variant, identified within a South African mixed ancestry population, substitution occupies less conformational clusters of folded states as compared to the wild-type and is destabilizing | Homo sapiens |
V231G | single nucleotide variant, identified within a South African mixed ancestry population. Less thermodynamically stable protein structure and is predicted, and affecting NAT1 protein function | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P18440 | - |
- |