Any feedback?
Literature summary for 2.3.1.206 extracted from
- Synthetic pathway for the production of olivetolic acid in Escherichia coli (2018), ACS Synth. Biol., 7, 1886-1896 .
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | a synthetic pathway for the production of olivetolic acid in Escherichia coli is developed. Through combining OLA synthase and OLA cyclase expression with the required modules of a beta-oxidation reversal for hexanoyl-CoAgeneration, we demonstrate the in vivo synthesis of olivetolic acid from a single carbon source. The integration of additional auxiliary enzymes to increase hexanoyl-CoA and malonyl-CoA, along with evaluation of varying fermentation conditions enabled the synthesis of 80 mg/l olivetolic acid. Olivetolic acid has various pharmacological activities | Cannabis sativa |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Cannabis sativa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cannabis sativa | B1Q2B6 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| OLA synthase | - |
Cannabis sativa |
| OLS | - |
Cannabis sativa |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
