Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe | corrinoid/iron-sulfur protein required | Moorella thermoacetica |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Moorella thermoacetica | key enzyme in the autotrophic acetyl-CoA pathway, i.e. Wood pathway, enzyme catalyses the final steps in this pathway | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Moorella thermoacetica | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
acetyl-CoA + a [Co(I) corrinoid Fe-S protein] = CO + CoA + a [methyl-Co(III) corrinoid Fe-S protein] | pathway | Moorella thermoacetica |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CH3-tetrahydrofolate + CO + HS-CoA | The methyltransferase catalyses the reaction of CH3-H4folate with the corrinoid/iron-sulfur protein to form a methylcobalt species. The Ni/Fe-S enzyme CO dehydrogease then catalyses the final steps in the formation of acetyl-CoA. | Moorella thermoacetica | CH3-CO-S-CoA + tetrahydrofolate | - |
? | |
CO + methyl-X + HS-CoA | - |
Moorella thermoacetica | CH3-CO-S-CoA + HX | - |
? | |
additional information | key enzyme in the autotrophic acetyl-CoA pathway, i.e. Wood pathway, enzyme catalyses the final steps in this pathway | Moorella thermoacetica | ? | - |
? |