Application | Comment | Organism |
---|---|---|
drug development | the enzyme is an important target for design of environmental-benign herbicides | Brassica rapa subsp. oleifera |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2E)-3,3'-dioxo-1,1',3,3'-tetrahydro-2,2'-biindole-5,5'-disulfonate | inhibition profile and inhibition of root growth, overview | Brassica rapa subsp. oleifera | |
3-(7H-cyclopenta[b]pyridin-5-yl)-N-[(2-nitrophenyl)sulfanyl]alanine | inhibition profile and inhibition of root growth, overview | Brassica rapa subsp. oleifera | |
6,6'-disulfanediyldipyridine-3-carboxylic acid | inhibition profile and inhibition of root growth, overview | Brassica rapa subsp. oleifera | |
chlorimuron ethyl | a sulfonylurea herbicide | Brassica rapa subsp. oleifera | |
imazapyr | an imidazolinone herbicide | Brassica rapa subsp. oleifera | |
additional information | computational database screening for non-sulfonylurea inhibitors of AHAS, overview | Brassica rapa subsp. oleifera |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Brassica rapa subsp. oleifera |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
pyruvate | Brassica rapa subsp. oleifera | the enzyme catalyzes the first committed step in the biosynthesis of valine, leucine, and isoleucine | 2-acetolactate + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Brassica rapa subsp. oleifera | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
root | - |
Brassica rapa subsp. oleifera | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pyruvate | - |
Brassica rapa subsp. oleifera | 2-acetolactate + CO2 | - |
? | |
pyruvate | the enzyme catalyzes the first committed step in the biosynthesis of valine, leucine, and isoleucine | Brassica rapa subsp. oleifera | 2-acetolactate + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
acetohydroxy acid synthase | - |
Brassica rapa subsp. oleifera |
AHAS | - |
Brassica rapa subsp. oleifera |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Brassica rapa subsp. oleifera |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Brassica rapa subsp. oleifera |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Brassica rapa subsp. oleifera | |
thiamine diphosphate | - |
Brassica rapa subsp. oleifera |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0152 | - |
6,6'-disulfanediyldipyridine-3-carboxylic acid | pH 7.0, 37°C | Brassica rapa subsp. oleifera | |
0.0421 | - |
(2E)-3,3'-dioxo-1,1',3,3'-tetrahydro-2,2'-biindole-5,5'-disulfonate | pH 7.0, 37°C | Brassica rapa subsp. oleifera | |
0.0907 | - |
3-(7H-cyclopenta[b]pyridin-5-yl)-N-[(2-nitrophenyl)sulfanyl]alanine | pH 7.0, 37°C | Brassica rapa subsp. oleifera |