Literature summary for 2.1.1.348 extracted from

Yao, Q.; Sang, L.; Lin, M.; Yin, X.; Dong, W.; Gong, Y.; Zhou, B.
Mettl3-Mettl14 methyltransferase complex regulates the quiescence of adult hematopoietic stem cells (2018), Cell Res., 28, 952-954 .

Search for more literature for 2.1.1.348

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	Q8C3P7 and Q3UIK4	Q8C3P7: METTL3, N6-adenosine-methyltransferase 70 kDa subunit. Q3UIK4: METTL14, N6-adenosine-methyltransferase non-catalytic subunit	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
hematopoietic stem cell	-	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
Mettl3-Mettl14 methyltransferase complex	-	Mus musculus

General Information

General Information	Comment	Organism
malfunction	the accumulation of phenotypic hematopoietic stem cells in Mettl3-deficient mice is most likely due to a loss of hematopoietic stem cell quiescence	Mus musculus
physiological function	Mettl3-Mettl14 methyltransferase complex regulates the quiescence of adult hematopoietic stem cells. It functions through promoting the expression of genes that maintain hematopoietic stem cell quiescence	Mus musculus

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Release 2023.1 (January 2023)