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Literature summary for 2.1.1.33 extracted from

  • Thongdee, N.; Jaroensuk, J.; Atichartpongkul, S.; Chittrakanwong, J.; Chooyoung, K.; Srimahaeak, T.; Chaiyen, P.; Vattanaviboon, P.; Mongkolsuk, S.; Fuangthong, M.
    TrmB, a tRNA m7G46 methyltransferase, plays a role in hydrogen peroxide resistance and positively modulates the translation of katA and katB mRNAs in Pseudomonas aeruginosa (2019), Nucleic Acids Res., 47, 9271-9281 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.33

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa Q02U31
-
-
Pseudomonas aeruginosa UCBPP-PA14 Q02U31
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no substrates: tRNALeu/CAG, tRNALeu/GAG, and tRNASec(p)/UCA Pseudomonas aeruginosa ?
-
-
additional information no substrates: tRNALeu/CAG, tRNALeu/GAG, and tRNASec(p)/UCA Pseudomonas aeruginosa UCBPP-PA14 ?
-
-
S-adenosyl-L-methionine + guanine46 in RNAAla/UGC
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in RNAAla/UGC
-
 ?
S-adenosyl-L-methionine + guanine46 in RNAAla/UGC
-
 Pseudomonas aeruginosa UCBPP-PA14 S-adenosyl-L-homocysteine + N7-methylguanine46 in RNAAla/UGC
-
 ?
S-adenosyl-L-methionine + guanine46 in RNAArg/ACG
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in RNAArg/ACG
-
 ?
S-adenosyl-L-methionine + guanine46 in RNAArg/ACG
-
 Pseudomonas aeruginosa UCBPP-PA14 S-adenosyl-L-homocysteine + N7-methylguanine46 in RNAArg/ACG
-
 ?
S-adenosyl-L-methionine + guanine46 in RNAArg/CCG
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in RNAArg/CCG
-
 ?
S-adenosyl-L-methionine + guanine46 in RNAArg/CCG
-
 Pseudomonas aeruginosa UCBPP-PA14 S-adenosyl-L-homocysteine + N7-methylguanine46 in RNAArg/CCG
-
 ?
S-adenosyl-L-methionine + guanine46 in RNAArg/CCU
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in RNAArg/CCU
-
 ?
S-adenosyl-L-methionine + guanine46 in RNAArg/CCU
-
 Pseudomonas aeruginosa UCBPP-PA14 S-adenosyl-L-homocysteine + N7-methylguanine46 in RNAArg/CCU
-
 ?
S-adenosyl-L-methionine + guanine46 in RNAArg/UCU
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in RNAArg/UCU
-
 ?
S-adenosyl-L-methionine + guanine46 in RNAAsn/GUU
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in RNAAsn/GUU
-
 ?
S-adenosyl-L-methionine + guanine46 in RNAAsp/GUC
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in RNAAsp/GUC
-
 ?
S-adenosyl-L-methionine + guanine46 in RNAGly/GCC
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in RNAGly/GCC
-
 ?
S-adenosyl-L-methionine + guanine46 in RNAHis/GUG
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in RNAHis/GUG
-
 ?
S-adenosyl-L-methionine + guanine46 in RNAIle/GAU
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in RNAIle/GAU
-
 ?
S-adenosyl-L-methionine + guanine46 in RNALys/UUU
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in RNALys/UUU
-
 ?
S-adenosyl-L-methionine + guanine46 in RNAThr/CGU
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in RNAThr/CGU
-
 ?
S-adenosyl-L-methionine + guanine46 in RNAVal/GAC
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in RNAVal/GAC
-
 ?
S-adenosyl-L-methionine + guanine46 in tRNAAla/GGC
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in tRNAAla/GGC
-
 ?
S-adenosyl-L-methionine + guanine46 in tRNAMet/CAU
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in tRNAMet/CAU
-
 ?
S-adenosyl-L-methionine + guanine46 in tRNAPhe/GAA
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in tRNAPhe/GAA
-
 ?
S-adenosyl-L-methionine + guanine46 in tRNAPro/CGG
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in tRNAPro/CGG
-
 ?
S-adenosyl-L-methionine + guanine46 in tRNAPro/GGG
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in tRNAPro/GGG
-
 ?
S-adenosyl-L-methionine + guanine46 in tRNAPro/UGG
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in tRNAPro/UGG
-
 ?
S-adenosyl-L-methionine + guanine46 in tRNAThr/GGU
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in tRNAThr/GGU
-
 ?
S-adenosyl-L-methionine + guanine46 in tRNAThr/UGU
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in tRNAThr/UGU
-
 ?
S-adenosyl-L-methionine + guanine46 in tRNATrp/CCA
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in tRNATrp/CCA
-
 ?
S-adenosyl-L-methionine + guanine46 in tRNAVal/UAC
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine46 in tRNAVal/UAC
-
 ?

Synonyms

Synonyms Comment Organism
PA14_05000
-
 Pseudomonas aeruginosa

General Information

General Information Comment Organism
physiological function the abundance of m7G in the tRNA extracted from trmB complemented strain is about 50% lower than the abundance of m7G extracted from the wild type strain. Pseudomonas aeruginosa shows a tRNA modification-mediated translational response to H2O2. Loss of TrmB has a strong negative effect on the translation of Phe- and Asp-enriched mRNAs. The TrmB-mediated m7G modification modulates the expression of the catalase genes KatA and KatB, which are enriched with Phe/Asp codons at the translational level. In response to H2O2 exposure, the level of m7G modification increases, consistent with the increased translation efficiency of Phe- and Asp-enriched mRNAs. Inactivation of TrmB leads to decreased KatA and KatB protein abundance and decreased catalase activity, resulting in H2O2-sensitive phenotype Pseudomonas aeruginosa