Cloned (Comment) | Organism |
---|---|
expression in Streptomyces albus | Streptomyces olivaceus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
41180 | - |
x * 41180, calculated from sequence | Streptomyces olivaceus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C | Streptomyces olivaceus | the enzyme is involved in the biosynthesis of the polyketide elloramycin | S-adenosyl-L-homocysteine + 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C | - |
? | |
S-adenosyl-L-methionine + 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C | Streptomyces olivaceus Tü2353 | the enzyme is involved in the biosynthesis of the polyketide elloramycin | S-adenosyl-L-homocysteine + 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces olivaceus | Q9AJU2 | - |
- |
Streptomyces olivaceus Tü2353 | Q9AJU2 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C | the enzyme is involved in the biosynthesis of the polyketide elloramycin | Streptomyces olivaceus | S-adenosyl-L-homocysteine + 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C | - |
? | |
S-adenosyl-L-methionine + 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C | using as biotransformation host strain EPM1 (expressing elmMI) about 24% of the precursor 8-demethyl-8-alpha-L-rhamnosyl tetracenomycin C is converted into 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C. No activity with substrates lacking the hydroxy group at C-2' (8-demethyl-8-alpha-L-oleandrosyl tetracenomycin C or 8-demethyl-8-alpha-L-olivosyl tetracenomycin C) | Streptomyces olivaceus | S-adenosyl-L-homocysteine + 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C | - |
? | |
S-adenosyl-L-methionine + 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C | the enzyme is involved in the biosynthesis of the polyketide elloramycin | Streptomyces olivaceus Tü2353 | S-adenosyl-L-homocysteine + 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C | - |
? | |
S-adenosyl-L-methionine + 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C | using as biotransformation host strain EPM1 (expressing elmMI) about 24% of the precursor 8-demethyl-8-alpha-L-rhamnosyl tetracenomycin C is converted into 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C. No activity with substrates lacking the hydroxy group at C-2' (8-demethyl-8-alpha-L-oleandrosyl tetracenomycin C or 8-demethyl-8-alpha-L-olivosyl tetracenomycin C) | Streptomyces olivaceus Tü2353 | S-adenosyl-L-homocysteine + 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 41180, calculated from sequence | Streptomyces olivaceus |
Synonyms | Comment | Organism |
---|---|---|
ElmMI | - |
Streptomyces olivaceus |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is involved in the biosynthesis of the polyketide elloramycin | Streptomyces olivaceus |