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Literature summary for 2.1.1.232 extracted from
- Biosynthesis of bioactive isokaemferide from naringenin in Escherichia coli (2019), J. Appl. Biol. Chem., 62, 1-6 .
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | production of sakuranetin (7-O-methylnaringenin) and ponciretin (4-O-methylnaringenin) in Escherichia coli by reconstruction of the naringenin biosynthesis pathway. Engineering the shikimic acid pathway, and overexpression of several genes for the biosynthesis of ponciretin and sakuranetin such as tyrosine ammonia lyase, 4-coumaroyl CoA ligase, chalcone synthase, and O-methyltransferase and deletion of isocitrate dehydrogenase finally gives ponciretin and sakuranetin from glucose in Escherichia coli at the concentration of 42.5 mg/l and 40.1 mg/l, respectively | Oryza sativa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryza sativa | - |
cv. Nakdong | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + (2S)-naringenin | - |
Oryza sativa | S-adenosyl-L-homocysteine + (2S)-sakuranetin | - |
? |  |
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Release 2023.1 (January 2023)
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