Crystallization (Comment) | Organism |
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crystal structures of apo-form RlmCD and its complex with SAH. A long linker in the central domain of RlmCD is the key factor in determining its substrate selectivity | Streptococcus pneumoniae |
Protein Variants | Comment | Organism |
---|---|---|
additional information | both full-length RlmCD and its shorter construct RlmCDs (residue 1-454) exhibit strong U74 methyltransferase activity when compared with the glutamine mutant of E443 | Streptococcus pneumoniae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
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Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus pneumoniae | Q97R12 | introduces C5 methylation at both U747 and U1939 of the 23S ribosomal RNA, i. e. catalyzes both the reactions of EC 2.1.1.189 and EC 2.1.1.190; serotype 4 | - |
Streptococcus pneumoniae ATCC BAA-334 | Q97R12 | introduces C5 methylation at both U747 and U1939 of the 23S ribosomal RNA, i. e. catalyzes both the reactions of EC 2.1.1.189 and EC 2.1.1.190; serotype 4 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | replacement of U747 in substrate 5'-740GGCACGUUGAAAAGUGCC757-3' by A, C, or G completely abolishes methylation | Streptococcus pneumoniae | ? | - |
- |
|
additional information | replacement of U747 in substrate 5'-740GGCACGUUGAAAAGUGCC757-3' by A, C, or G completely abolishes methylation | Streptococcus pneumoniae ATCC BAA-334 | ? | - |
- |
|
S-adenosyl-L-methionine + 5'-740GGCACGUUGAAAAGUGCC757-3' | 18-mer RNA analogue of the 23S rRNA helix 35 | Streptococcus pneumoniae | S-adenosyl-L-homocysteine + 5'-740GGCACGUm5UGAAAAGUGCC757-3' | - |
? | |
S-adenosyl-L-methionine + 5'-740GGCACGUUGAAAAGUGCC757-3' | 18-mer RNA analogue of the 23S rRNA helix 35 | Streptococcus pneumoniae ATCC BAA-334 | S-adenosyl-L-homocysteine + 5'-740GGCACGUm5UGAAAAGUGCC757-3' | - |
? |
Synonyms | Comment | Organism |
---|---|---|
RlmCD | - |
Streptococcus pneumoniae |
SP_1029 | - |
Streptococcus pneumoniae |