Application | Comment | Organism |
---|---|---|
medicine | dihydrolipoyl dehydrogenase is an important source of reactive oxygen species leading to life span limitation | Saccharomyces cerevisiae |
Protein Variants | Comment | Organism |
---|---|---|
additional information | deletion of the LPD1 gene prevents oxidative stress in npt1DELTA and bna6DELTA mutants | Saccharomyces cerevisiae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | inhibited by caloric restriction | Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Saccharomyces cerevisiae | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dihydrolipoamide + NAD+ | - |
Saccharomyces cerevisiae | lipoamide + NADH + H+ | - |
? | |
O2 + NADH + H+ | - |
Saccharomyces cerevisiae | H2O2 + NAD+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
dihydrolipoamide dehydrogenase | - |
Saccharomyces cerevisiae |
LPD1 | - |
Saccharomyces cerevisiae |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Saccharomyces cerevisiae | |
NADH | - |
Saccharomyces cerevisiae |