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Literature summary for 1.6.2.4 extracted from

  • Shi, L.; Li, W.; Dong, Y.; Shi, Y.; Zhou, Y.; Liao, X.
    NADPH-cytochrome P450 reductase potentially involved in indoxacarb resistance in Spodoptera litura (2021), Pestic. Biochem. Physiol., 173, 104775 .
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Spodoptera litura A0A5B8YSR6
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Source Tissue

Source Tissue Comment Organism Textmining
fat body high expression level Spodoptera litura
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midgut high expression level Spodoptera litura
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additional information protein is detected in all tested developmental stages and tissues, but highly expressed in third-, fourth-, and fifth-instar larvae, and in midgut and fat body Spodoptera litura
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Expression

Organism Comment Expression
Spodoptera litura both transcripts CPR-X1 and CPR-X2 are upregulated and more inducible when treated with indoxacarb in the indoxacarb-resistant strain. The relative expression, up-regulation and induction of CPR-X1 are all higher than those of CPR-X2 in the indoxacarb-resistant strain up

General Information

General Information Comment Organism
physiological function identification of 2 transcripts CPR-X1 and CPR-X2. The deduced protein of CPR-X1 contains all features (N-terminal membrane anchor, FMN, FAD and NADP binding domains, FAD binding motif, and catalytic residues). No N-terminal member anchor and a shorter FMN binding region have been identified in the deduced protein of CPR-X2. SPR-X1 with the N-terminal membrane anchor is the major CPR potentially involved in Spodoptera litura indoxacarb resistance Spodoptera litura