Protein Variants | Comment | Organism |
---|---|---|
additional information | replacement of all seven cysteine residues, no gross effect is observed on FMN and FAD binding and electron transfer from NADPH. Cytochrome c reduction is decreased to 2% of wild-type. Introduction of Cys residues S9C, S32C, S55C, T668C to the Cys-less mutant shows substantial conformational changes upon membrane reconstitution of mutant, while liposome insertion has little effect on the T668C | Homo sapiens |
additional information | the deletion of more than 29 residues from the N-terminus of CYPOR decreases cytochrome P450 activity concomitant with alterations in electrophoretic mobility and an increased resistance to protease digestion. The altered kinetic properties of these mutants are consistent with electron transfer through random collisions rather than via formation of a stable CYPOR-P450 complex | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P16435 | - |
- |
Subunits | Comment | Organism |
---|---|---|
? | x * 77200, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
CYPOR | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | after replacement of all seven cysteine residues, no gross effect is observed on FMN and FAD binding and electron transfer from NADPH | Homo sapiens | |
FMN | after replacement of all seven cysteine residues, no gross effect is observed on FMN and FAD binding and electron transfer from NADPH | Homo sapiens |