Literature summary for 1.14.14.79 extracted from

Fer, M.; Corcos, L.; Dreano, Y.; Plee-Gautier, E.; Sala�n, J.; Berthou, F.; Amet, Y.
Cytochromes P450 from family 4 are the main omega hydroxylating enzymes in humans: CYP4F3B is the prominent player in PUFA metabolism (2008), J. Lipid Res., 49, 2379-2389.

Search for more literature for 1.14.14.79

Inhibitors

Inhibitors	Comment	Organism	Structure
docosahexaenoic acid	10 microM, 70% inhibition of arachidonic acid metabolism	Homo sapiens
eicosapentaenoic acid	10 microM, 56% inhibition of arachidonic acid metabolism	Homo sapiens
eicosatrienoic acid	10 microM, 32% inhibition of arachidonic acid metabolism	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q08477	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
docosahexaenoic acid + [reduced NADPH-hemoprotein reductase] + O2	-	Homo sapiens	22-hydroxydocosahexaenoic acid + [oxidized NADPH-hemoprotein reductase] + H2O	-	?
eicosapentaenoic acid + NADPH + H+ + O2	-	Homo sapiens	20-hydroxyeicosapentaenoic acid + NADP+ + H2O	-	?
eicosatrienoic acid + [reduced NADPH-hemoprotein reductase] + O2	-	Homo sapiens	20-hydroxyeicosatrienoic acid + [oxidized NADPH-hemoprotein reductase] + H2O	-	?

Synonyms

Synonyms	Comment	Organism
CYP4F3B	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)