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Literature summary for 1.14.14.171 extracted from

  • Moses, T.; Pollier, J.; Almagro, L.; Buyst, D.; Van Montagu, M.; Pedre๑o, M.; Martins, J.; Thevelein, J.; Goossens, A.
    Combinatorial biosynthesis of sapogenins and saponins in Saccharomyces cerevisiae using a C-16alpha hydroxylase from Bupleurum falcatum (2014), Proc. Natl. Acad. Sci. USA, 111, 1634-1639 .
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharomyces cerevisiae strain TM48 Bupleurum falcatum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
beta-amyrin + [reduced NADPH-hemoprotein reductase] + O2 Bupleurum falcatum
-
 16alpha-hydroxy-beta-amyrin + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Bupleurum falcatum
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
root
-
 Bupleurum falcatum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-amyrin + [reduced NADPH-hemoprotein reductase] + O2
-
 Bupleurum falcatum 16alpha-hydroxy-beta-amyrin + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
additional information no activity with lupeol Bupleurum falcatum ?
-
 ?

Synonyms

Synonyms Comment Organism
C-16alpha hydroxylase
-
 Bupleurum falcatum
CYP716Y1
-
 Bupleurum falcatum