Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-oxo acid derivatives | of the 3 branched chain amino acids | Saccharomyces pastorianus | |
2-oxoglutarate | mixed type inhibitor | Saccharomyces pastorianus | |
alpha-Ketoisocaproate | non competitive inhibition | Saccharomyces pastorianus | |
pyruvate | mixed type inhibitor | Saccharomyces pastorianus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial outer membrane | - |
Saccharomyces pastorianus | 5741 | - |
mitochondrion | - |
Saccharomyces pastorianus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces pastorianus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Saccharomyces pastorianus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-kynurenine + NADPH + O2 | - |
Saccharomyces pastorianus | 3-hydroxy-L-kynurenine + NADP+ + H2O | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Saccharomyces pastorianus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
4.2 | - |
alpha-Ketoisocaproate | inhibition for L-kynurenine | Saccharomyces pastorianus | |
8.3 | - |
alpha-Ketoisocaproate | inhibition for NADPH | Saccharomyces pastorianus |