Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hypothalamus | estradiol regulates the nitrergic system in the supraoptic and paraventricular hypothalamic nuclei under acute osmotic stress conditions, but the effects specifically depend on the anatomical subregions and different estrogen receptors | Rattus norvegicus | - |
General Information | Comment | Organism |
---|---|---|
physiological function | estradiol regulates the nitrergic system in the supraoptic and paraventricular hypothalamic nuclei under acute osmotic stress conditions, but the effects specifically depend on the anatomical subregions and different estrogen receptors. The inhibition of estrogen receptor alpha enhances the effect of 1.5 M NaCl injection, inducing a further decrease in the number of NADPH-diaphorase-positive cells. The estrogen receptor beta agonist enhances and the estrogen receptor beta antagonist blocks the effect of NaCl injection on the number of NADPH-diaphorase-positive neurons in the supraoptic hypothalamic nuclei and in the medial magnocellular subdivision of the paraventricular hypothalamic nuclei | Rattus norvegicus |