Application | Comment | Organism |
---|---|---|
medicine | systemic IDO activity, determined as the kynurenine/tryptophan ratio in serum, correlates with the presence of palpable tumor. IDO mediates immune suppression in the early stages of prostate cancer progression. IDO expression in the tumor tissue is irrelevant for transgenic adenocarcinoma of mouse prostate tumor incidence | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-tryptophan + O2 | Mus musculus | - |
N-formyl-L-kynurenine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
culture condition:CD31+ cell | - |
Mus musculus | - |
culture condition:CD31- cell | - |
Mus musculus | - |
lymph node | - |
Mus musculus | - |
prostate | - |
Mus musculus | - |
serum | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-tryptophan + O2 | - |
Mus musculus | N-formyl-L-kynurenine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
IDO | - |
Mus musculus |