Cloned (Comment) | Organism |
---|---|
expressed in HEK-293T cell | Mus musculus |
GST-fusioned protein, expressed in Escherichia coli, expressed in HEK-293T cell | Xenopus laevis |
GST-fusioned protein, expressed in Escherichia coli, expressed in HEK-293T cell | Danio rerio |
hexahistidyl tagged, expressed in Escherichia coli, expressed in HEK-293T cell | Ornithorhynchus anatinus |
hexahistidyl tagged, expressed in Escherichia coli, expressed in HEK-293T cell | Monodelphis domestica |
Protein Variants | Comment | Organism |
---|---|---|
H339A | used as negative control | Xenopus laevis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0063 | - |
L-tryptophan | - |
Monodelphis domestica | |
0.0191 | - |
L-tryptophan | - |
Mus musculus | |
0.0537 | - |
L-tryptophan | - |
Ornithorhynchus anatinus | |
11.7 | - |
L-tryptophan | - |
Xenopus laevis | |
28.2 | - |
L-tryptophan | - |
Danio rerio | |
54.1 | - |
L-tryptophan | - |
Mus musculus | |
60.7 | - |
L-tryptophan | - |
Monodelphis domestica | |
62.4 | - |
L-tryptophan | - |
Ornithorhynchus anatinus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Danio rerio | - |
- |
- |
Monodelphis domestica | B3Y9H8 | XM_001381865: predicted coding sequences from genomic sequences | - |
Monodelphis domestica | B3Y9H9 | also another splice-variant detected, XM_001381868: predicted coding sequences from genomic sequences | - |
Mus musculus | - |
- |
- |
Ornithorhynchus anatinus | B3Y9H6 | XM_001516468, XM_001521552: predicted coding sequences from genomic sequences | - |
Ornithorhynchus anatinus | B3Y9H7 | XM_001516116: predicted coding sequences from genomic sequences | - |
Xenopus laevis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Xenopus laevis |
- |
Danio rerio |
- |
Ornithorhynchus anatinus |
- |
Monodelphis domestica |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Ornithorhynchus anatinus | - |
liver | - |
Monodelphis domestica | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-tryptophan + O2 | - |
Mus musculus | N-formylkynurenine | - |
? | |
L-tryptophan + O2 | - |
Xenopus laevis | N-formylkynurenine | - |
? | |
L-tryptophan + O2 | - |
Danio rerio | N-formylkynurenine | - |
? | |
L-tryptophan + O2 | - |
Ornithorhynchus anatinus | N-formylkynurenine | - |
? | |
L-tryptophan + O2 | - |
Monodelphis domestica | N-formylkynurenine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
indoleamine 2,3-dioxygenase | - |
Mus musculus |
indoleamine 2,3-dioxygenase | - |
Ornithorhynchus anatinus |
indoleamine 2,3-dioxygenase | - |
Monodelphis domestica |
indoleamine 2,3-dioxygenase-2 | - |
Mus musculus |
indoleamine 2,3-dioxygenase-2 | - |
Xenopus laevis |
indoleamine 2,3-dioxygenase-2 | - |
Danio rerio |
indoleamine 2,3-dioxygenase-2 | - |
Ornithorhynchus anatinus |
indoleamine 2,3-dioxygenase-2 | - |
Monodelphis domestica |
proto-indoleamine 2,3-dioxygenase | - |
Mus musculus |
proto-indoleamine 2,3-dioxygenase | - |
Xenopus laevis |
proto-indoleamine 2,3-dioxygenase | - |
Danio rerio |
proto-indoleamine 2,3-dioxygenase | - |
Ornithorhynchus anatinus |
proto-indoleamine 2,3-dioxygenase | - |
Monodelphis domestica |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.9 | - |
L-tryptophan | - |
Monodelphis domestica | |
1.8 | - |
L-tryptophan | - |
Mus musculus | |
2.2 | - |
L-tryptophan | - |
Xenopus laevis | |
2.6 | - |
L-tryptophan | - |
Danio rerio | |
2.9 | - |
L-tryptophan | - |
Ornithorhynchus anatinus | |
4.3 | - |
L-tryptophan | - |
Ornithorhynchus anatinus | |
16.8 | - |
L-tryptophan | - |
Mus musculus | |
19 | - |
L-tryptophan | - |
Monodelphis domestica |