Application | Comment | Organism |
---|---|---|
medicine | yellowing of the aged lens may be preventable by drug-induced suppression of IDO activity | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Trp + O2 | Homo sapiens | IDO is the first enzyme in UV-filter pathway. UV-filter biosynthesis is active even in aged lenses | L-formylkynurenine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lens | enzyme activity is detected in all lenses ranging from 26 to 80 years and there are no clear relationship of IDO activity with age | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Trp + O2 | IDO is the first enzyme in UV-filter pathway. UV-filter biosynthesis is active even in aged lenses | Homo sapiens | L-formylkynurenine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
IDO | - |
Homo sapiens |
indoleamine 2,3-dioxygenase | - |
Homo sapiens |