Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CuCl2 | 10 mM, 40% inhibition | Cavia porcellus | |
FeCl3 | 10 mM, 54% inhibition | Cavia porcellus | |
p-chloromercuribenzoate | 10 mM, strong inhibition, 5% residual activity is reversed to 65% activity by either 1 mM glutathione or cysteine | Cavia porcellus | |
Pb(NO3)2 | 10 mM, 30% inhibition | Cavia porcellus | |
Sodium amytal | 10 mM, 25% inhibition | Cavia porcellus | |
Sodium cyanide | 10 mM, progressive and marked inhibition | Cavia porcellus | |
ZnCl2 | 10 mM, 90% inhibition | Cavia porcellus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0596 | - |
testosterone | enzyme activity in microsomal fraction after centrifugation | Cavia porcellus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Cavia porcellus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
17beta-estradiol + NADP+ | Cavia porcellus | - |
estrone + NADPH | - |
r | |
testosterone + NADP+ | Cavia porcellus | - |
androst-4-ene-3,17-dione + NADPH + H+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Cavia porcellus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
96.5 | - |
enzyme activity in microsomal fraction after centrifugation | Cavia porcellus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
17beta-estradiol + NADP+ | - |
Cavia porcellus | estrone + NADPH | - |
r | |
testosterone + NADP+ | - |
Cavia porcellus | androst-4-ene-3,17-dione + NADPH + H+ | - |
r |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
10 | - |
sharp drop of activity above | Cavia porcellus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
8.5 | 10.5 | - |
Cavia porcellus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Cavia porcellus |