Activating Compound | Comment | Organism | Structure |
---|---|---|---|
defatted serum albumin | only with long-chain e.g. C16 3-ketoacyl-CoA, in concentrations lower than 0.6 mg/ml | Rattus norvegicus | |
defatted serum albumin | only with long-chain e.g. C16 3-ketoacyl-CoA, in concentrations lower than 0.6 mg/ml | Oryctolagus cuniculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
defatted serum albumin | only with long-chain e.g. C16 3-ketoacyl-CoA, in concentrations higher than 0.6 mg/ml | Oryctolagus cuniculus | |
defatted serum albumin | only with long-chain e.g. C16 3-ketoacyl-CoA, in concentrations higher than 0.6 mg/ml | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial inner membrane | - |
Rattus norvegicus | 5743 | - |
mitochondrial inner membrane | - |
Oryctolagus cuniculus | 5743 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
186000 | - |
liver, gel filtration | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
neonatal | - |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brown adipose tissue | - |
Oryctolagus cuniculus | - |
heart | - |
Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
it is specific for long chain substrate and has maximum activity with 3-ketohexadecanoyl-CoA | Rattus norvegicus |
additional information | - |
it is specific for long chain substrate and has maximum activity with 3-ketohexadecanoyl-CoA | Oryctolagus cuniculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-ketohexadecanoyl-CoA + NADH | - |
Rattus norvegicus | 3-hydroxyhexadecanoyl-CoA + NAD+ | - |
? | |
3-ketohexadecanoyl-CoA + NADH | - |
Oryctolagus cuniculus | 3-hydroxyhexadecanoyl-CoA + NAD+ | - |
? | |
3-ketohexanoyl-CoA + NADH | - |
Rattus norvegicus | 3-hydroxyhexanoyl-CoA + NAD+ | - |
? | |
3-ketohexanoyl-CoA + NADH | - |
Oryctolagus cuniculus | 3-hydroxyhexanoyl-CoA + NAD+ | - |
? | |
3-oxodecanoyl-CoA + NADH | - |
Rattus norvegicus | 3-hydroxydecanoyl-CoA + NAD+ | - |
? | |
3-oxodecanoyl-CoA + NADH | - |
Oryctolagus cuniculus | 3-hydroxydecanoyl-CoA + NAD+ | - |
? | |
acetoacetyl-CoA + NADH + H+ | - |
Rattus norvegicus | 3-hydroxybutyryl-CoA + NAD+ | - |
? | |
acetoacetyl-CoA + NADH + H+ | - |
Oryctolagus cuniculus | 3-hydroxybutyryl-CoA + NAD+ | - |
? | |
additional information | has also enoyl-CoA-hydratase activity | Rattus norvegicus | additional information | - |
? | |
additional information | has also enoyl-CoA-hydratase activity | Oryctolagus cuniculus | additional information | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Rattus norvegicus | |
NAD+ | - |
Oryctolagus cuniculus | |
NADH | - |
Rattus norvegicus | |
NADH | - |
Oryctolagus cuniculus |