Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | - |
Homo sapiens | |
2,2'-bipyridine | - |
Homo sapiens | |
4-Methylpyrazole | poor inhibitor, class II isoenzyme | Homo sapiens | |
EDTA | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.007 | - |
benzyl alcohol | 0.1 M glycine-NaOH buffer, pH 10.0, 25°C | Homo sapiens | |
0.007 | - |
Octanol | 0.1 M glycine-NaOH buffer, pH 10.0, 25°C | Homo sapiens | |
0.032 | - |
3-Phenyl-1-propanol | 0.1 M glycine-NaOH buffer, pH 10.0, 25°C | Homo sapiens | |
0.034 | - |
Vanillyl alcohol | 0.1 M glycine-NaOH buffer, pH 10.0, 25°C | Homo sapiens | |
0.06 | - |
16-hydroxyhexadecanoate | 0.1 M glycine-NaOH buffer, pH 10.0, 25°C | Homo sapiens | |
0.09 | - |
Pentanol | 0.1 M glycine-NaOH buffer, pH 10.0, 25°C | Homo sapiens | |
0.2 | - |
tryptophol | 0.1 M glycine-NaOH buffer, pH 10.0, 25°C | Homo sapiens | |
0.23 | - |
12-hydroxydodecanoate | 0.1 M glycine-NaOH buffer, pH 10.0, 25°C | Homo sapiens | |
120 | - |
ethanol | 0.1 M glycine-NaOH buffer, pH 10.0, 25°C | Homo sapiens | |
210 | - |
Cyclohexanol | 0.1 M glycine-NaOH buffer, pH 10.0, 25°C | Homo sapiens | |
290 | - |
ethylene glycol | 0.1 M glycine-NaOH buffer, pH 10.0, 25°C | Homo sapiens | |
310 | - |
2-deoxy-D-ribose | 0.1 M glycine-NaOH buffer, pH 10.0, 25°C | Homo sapiens | |
560 | - |
2-propanol | 0.1 M glycine-NaOH buffer, pH 10.0, 25°C | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
42000 | - |
x * 42000, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
class II isoenzyme: pi-ADH | - |
Purification (Comment) | Organism |
---|---|
class II isoenzyme: pi-ADH | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1.47 | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
4°C, pH 7.5, stable for 2-3 weeks | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
12-hydroxydodecanoate + NAD+ | - |
Homo sapiens | 12-oxododecanoic acid + NADH | - |
? | |
16-hydroxyhexadecanoate + NAD+ | - |
Homo sapiens | 16-oxohexadecanoic acid + NADH | - |
? | |
2-deoxy-D-ribose + NAD+ | - |
Homo sapiens | ? + NADH | - |
? | |
3-phenyl-1-propanol + NAD+ | - |
Homo sapiens | 3-phenyl-1-propanone + NADH | - |
? | |
benzyl alcohol + NAD+ | - |
Homo sapiens | benzaldehyde + NADH | - |
? | |
cyclohexanol + NAD+ | - |
Homo sapiens | cyclohexanone + NADH | - |
? | |
ethanol + NAD+ | - |
Homo sapiens | acetaldehyde + NADH | - |
? | |
ethylene glycol + NAD+ | - |
Homo sapiens | ? + NADH | - |
? | |
methanol + NAD+ | activity detected with class II isoenzyme pi-ADH | Homo sapiens | formaldehyde + NADH + H+ | - |
? | |
octan-1-ol + NAD+ | - |
Homo sapiens | n-octanal + NADH | - |
? | |
pentanal + NAD+ | - |
Homo sapiens | pentanone + NADH | - |
? | |
propan-2-ol + NAD+ | - |
Homo sapiens | acetone + NADH | - |
? | |
tryptophol + NAD+ | - |
Homo sapiens | ? + NADH | - |
? | |
vanillyl alcohol + NAD+ | - |
Homo sapiens | vanillin + NADH | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 42000, SDS-PAGE | Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.583 | - |
Cyclohexanol | - |
Homo sapiens | |
0.75 | - |
2-propanol | - |
Homo sapiens | |
0.75 | - |
ethylene glycol | - |
Homo sapiens | |
1.83 | - |
tryptophol | - |
Homo sapiens | |
2.83 | - |
2-deoxy-D-ribose | - |
Homo sapiens | |
4 | - |
12-hydroxydodecanoate | - |
Homo sapiens | |
6.17 | - |
16-hydroxyhexadecanoate | - |
Homo sapiens | |
7.5 | - |
3-Phenyl-1-propanol | - |
Homo sapiens | |
7.83 | - |
ethanol | - |
Homo sapiens | |
8 | - |
Pentanol | - |
Homo sapiens | |
8.33 | - |
Octanol | - |
Homo sapiens | |
8.67 | - |
Vanillyl alcohol | - |
Homo sapiens | |
9.17 | - |
benzyl alcohol | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
10.4 | - |
- |
Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
8 | 12 | about 30% of maximal activity at pH 8.0 and at pH 12.0 | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens | |
NADH | - |
Homo sapiens |