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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD
+
or NADP
+
as acceptor
1.1.2 With a cytochrome as acceptor
1.1.3 With oxygen as acceptor
1.1.4 With a disulfide as acceptor
1.1.5 With a quinone or similar compound as acceptor
1.1.7 With an iron-sulfur protein as acceptor
1.1.9 With a copper protein as acceptor
1.1.9.1 alcohol dehydrogenase (azurin)
1.1.98 With other, known, physiological acceptors
1.1.99 With unknown physiological acceptors
1.2 Acting on the aldehyde or oxo group of donors
1.3 Acting on the CH-CH group of donors
1.4 Acting on the CH-NH
2
group of donors
1.5 Acting on the CH-NH group of donors
1.6 Acting on NADH or NADPH
1.7 Acting on other nitrogenous compounds as donors
1.8 Acting on a sulfur group of donors
1.9 Acting on a heme group of donors
1.10 Acting on diphenols and related substances as donors
1.11 Acting on a peroxide as acceptor
1.12 Acting on hydrogen as donor
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.15 Acting on superoxide as acceptor
1.16 Oxidizing metal ions
1.17 Acting on CH or CH
2
groups
1.18 Acting on iron-sulfur proteins as donors
1.19 Acting on reduced flavodoxin as donor
1.20 Acting on phosphorus or arsenic in donors
1.21 Catalysing the reaction X-H + Y-H = X-Y
1.22 Acting on halogen in donors
1.23 Reducing C-O-C group as acceptor
1.97 Other oxidoreductases
1.97.1 Sole sub-subclass for oxidoreductases that do not belong in the other subclasses
1.98 Enzymes using H
2
as reductant (deleted subclass)
1.99 Other enzymes using O
2
as oxidant (deleted subclass)
2 Transferases
3 Hydrolases
4 Lyases
5 Isomerases
5.1 Racemases and epimerases
5.2
cis-trans-
Isomerases
5.3 Intramolecular oxidoreductases
5.4 Intramolecular transferases
5.4.1 Transferring acyl groups
5.4.2 Phosphotransferases (phosphomutases)
5.4.3 Transferring amino groups
5.4.4 Transferring hydroxy groups
5.4.99 Transferring other groups
5.4.99.1 methylaspartate mutase
5.4.99.2 methylmalonyl-CoA mutase
5.4.99.3 2-acetolactate mutase
5.4.99.4 2-methyleneglutarate mutase
5.4.99.5 chorismate mutase
5.4.99.6 created 1972, deleted 2003
5.4.99.7 lanosterol synthase
5.4.99.8 cycloartenol synthase
5.4.99.9 UDP-galactopyranose mutase
5.4.99.10 created 1984, deleted 1992
5.4.99.11 isomaltulose synthase
5.4.99.12 tRNA pseudouridine
38-40
synthase
5.4.99.13 isobutyryl-CoA mutase
5.4.99.14 4-carboxymethyl-4-methylbutenolide mutase
5.4.99.15 (1→4)-α-
D
-glucan 1-α-
D
-glucosylmutase
5.4.99.16 maltose α-
D
-glucosyltransferase
5.4.99.17 squalene—hopene cyclase
5.4.99.18 5-(carboxyamino)imidazole ribonucleotide mutase
5.4.99.19 16S rRNA pseudouridine
516
synthase
5.4.99.20 23S rRNA pseudouridine
2457
synthase
5.4.99.21 23S rRNA pseudouridine
2604
synthase
5.4.99.22 23S rRNA pseudouridine
2605
synthase
5.4.99.23 23S rRNA pseudouridine
1911/1915/1917
synthase
5.4.99.24 23S rRNA pseudouridine
955/2504/2580
synthase
5.4.99.25 tRNA pseudouridine
55
synthase
5.4.99.26 tRNA pseudouridine
65
synthase
5.4.99.27 tRNA pseudouridine
13
synthase
5.4.99.28 tRNA pseudouridine
32
synthase
5.4.99.29 23S rRNA pseudouridine
746
synthase
5.4.99.30 UDP-arabinopyranose mutase
5.4.99.31 thalianol synthase
5.4.99.32 protostadienol synthase
5.4.99.33 cucurbitadienol synthase
5.4.99.34 germanicol synthase
5.4.99.35 taraxerol synthase
5.4.99.36 isomultiflorenol synthase
5.4.99.37 dammaradiene synthase
5.4.99.38 camelliol C synthase
5.4.99.39 β-amyrin synthase
5.4.99.40 α-amyrin synthase
5.4.99.41 lupeol synthase
5.4.99.42 tRNA pseudouridine
31
synthase
5.4.99.43 21S rRNA pseudouridine
2819
synthase
5.4.99.44 mitochondrial tRNA pseudouridine
27/28
synthase
5.4.99.45 tRNA pseudouridine
38/39
synthase
5.4.99.46 shionone synthase
5.4.99.47 parkeol synthase
5.4.99.48 achilleol B synthase
5.4.99.49 glutinol synthase
5.4.99.50 friedelin synthase
5.4.99.51 baccharis oxide synthase
5.4.99.52 α-seco-amyrin synthase
5.4.99.53 marneral synthase
5.4.99.54 β-seco-amyrin synthase
5.4.99.55 δ-amyrin synthase
5.4.99.56 tirucalladienol synthase
5.4.99.57 baruol synthase
5.4.99.58 methylornithine synthase
5.4.99.59 dTDP-fucopyranose mutase
5.4.99.60 cobalt-precorrin-8 methylmutase
5.4.99.61 precorrin-8X methylmutase
5.4.99.62
D
-ribose pyranase
5.4.99.63 ethylmalonyl-CoA mutase
5.4.99.64 2-hydroxyisobutanoyl-CoA mutase
5.4.99.65 pre-α-onocerin synthase
5.4.99.66 α-onocerin synthase
5.4.99.67 4-amino-4-deoxychorismate mutase
5.5 Intramolecular lyases
5.6 Isomerases altering macromolecular conformation
5.99 Other isomerases
6 Ligases
7 Translocases