EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
2.7.11.2 | [pyruvate dehydrogenase (acetyl-transferring)] kinase |
hepatoma cell |
Fao cell line |
661301 |
2.7.11.2 | [pyruvate dehydrogenase (acetyl-transferring)] kinase |
hepatoma cell |
PDK4 |
660642 |
2.7.11.20 | elongation factor 2 kinase |
hepatoma cell |
- |
761286 |
2.7.11.24 | mitogen-activated protein kinase |
hepatoma cell |
- |
491741 |
2.7.11.27 | [acetyl-CoA carboxylase] kinase |
hepatoma cell |
- |
760778 |
2.7.11.30 | receptor protein serine/threonine kinase |
hepatoma cell |
- |
665532 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
hepatoma cell |
- |
692267 |
2.7.4.6 | nucleoside-diphosphate kinase |
hepatoma cell |
in hepatocarcinoma derived cell lines, NME4 expression is lower in cell lines with high metastatic potential |
761777 |
2.7.4.8 | guanylate kinase |
hepatoma cell |
Morris 7793 or Dunning |
642686 |
2.7.7.19 | polynucleotide adenylyltransferase |
hepatoma cell |
- |
642938 |
2.7.7.19 | polynucleotide adenylyltransferase |
hepatoma cell |
Morris hepatoma tumor cells 3924A |
642946, 642951 |
2.7.7.19 | polynucleotide adenylyltransferase |
hepatoma cell |
Morris hepatomas 3924A and 7777, relative lack of poly(A) polymerase activity is partly due to decreased level of this enzyme in the tumors, but largely due to the nonavailability of the primer-binding sites on the solubilized enzyme and to occupation of the available binding sites with an ineffective primer |
642967 |
2.8.1.1 | thiosulfate sulfurtransferase |
hepatoma cell |
only about 20% of the activity of normal liver |
645502 |
2.8.2.1 | aryl sulfotransferase |
hepatoma cell |
- |
645675 |
2.8.2.14 | bile-salt sulfotransferase |
hepatoma cell |
- |
761727 |
2.8.2.2 | alcohol sulfotransferase |
hepatoma cell |
- |
761727 |
2.8.2.2 | alcohol sulfotransferase |
hepatoma cell |
SULT2B1b mRNA levels in clinical hepatocarcinoma tumor samples are higher than in the non-tumorous tissue adjacent to the tumors |
-, 760454 |
2.8.2.4 | estrone sulfotransferase |
hepatoma cell |
- |
760317 |
3.1.2.4 | 3-hydroxyisobutyryl-CoA hydrolase |
hepatoma cell |
46% reduced activity compared to healthy cells |
650865 |
3.1.2.6 | hydroxyacylglutathione hydrolase |
hepatoma cell |
Kirkman-Robbins hepatoma |
37413 |
3.1.2.6 | hydroxyacylglutathione hydrolase |
hepatoma cell |
Morris hepatoma cells 5123S |
37413 |
3.1.3.42 | [glycogen-synthase-D] phosphatase |
hepatoma cell |
- |
94864 |
3.1.3.46 | fructose-2,6-bisphosphate 2-phosphatase |
hepatoma cell |
- |
94932 |
3.1.3.9 | glucose-6-phosphatase |
hepatoma cell |
- |
649729, 750010 |
3.1.3.9 | glucose-6-phosphatase |
hepatoma cell |
hepatitis virus-induced hepatocellular carcinoma |
664672 |
3.1.4.11 | phosphoinositide phospholipase C |
hepatoma cell |
rapidly growing hepatoma 3924A |
135125 |
3.1.4.12 | sphingomyelin phosphodiesterase |
hepatoma cell |
- |
678142, 678957 |
3.1.4.37 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase |
hepatoma cell |
quantitative isozymes expression analysis in hepatoma cell lines |
730760 |
3.1.4.39 | alkylglycerophosphoethanolamine phosphodiesterase |
hepatoma cell |
- |
696397 |
3.1.4.50 | glycosylphosphatidylinositol phospholipase D |
hepatoma cell |
- |
691854 |
3.1.8.1 | aryldialkylphosphatase |
hepatoma cell |
- |
678489 |
3.2.1.113 | mannosyl-oligosaccharide 1,2-alpha-mannosidase |
hepatoma cell |
- |
646574 |
3.2.1.113 | mannosyl-oligosaccharide 1,2-alpha-mannosidase |
hepatoma cell |
HepG2, HepG2.2.15, AD38, and N10 |
752329 |
3.2.1.114 | mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase |
hepatoma cell |
- |
646574 |
3.2.1.130 | glycoprotein endo-alpha-1,2-mannosidase |
hepatoma cell |
clone 9 |
-, 646732 |
3.2.1.45 | glucosylceramidase |
hepatoma cell |
- |
751699 |
3.2.1.51 | alpha-L-fucosidase |
hepatoma cell |
not detected in adjacent tissue |
667006 |
3.3.2.10 | soluble epoxide hydrolase |
hepatoma cell |
- |
707633 |
3.3.2.9 | microsomal epoxide hydrolase |
hepatoma cell |
- |
708309 |
3.4.13.18 | cytosol nonspecific dipeptidase |
hepatoma cell |
- |
679269 |
3.4.17.22 | metallocarboxypeptidase D |
hepatoma cell |
overexpressed in hepatocellular carcinoma |
731593 |
3.4.21.1 | chymotrypsin |
hepatoma cell |
- |
680927 |
3.4.21.73 | u-Plasminogen activator |
hepatoma cell |
- |
731238, 731239 |
3.4.21.B27 | proprotein convertase 7 |
hepatoma cell |
- |
731888 |
3.4.22.56 | caspase-3 |
hepatoma cell |
- |
647611, 710588, 753878 |
3.4.22.59 | caspase-6 |
hepatoma cell |
- |
697089 |
3.4.22.61 | caspase-8 |
hepatoma cell |
- |
664969, 696137, 710203 |
3.4.22.63 | caspase-10 |
hepatoma cell |
- |
710209 |
3.4.22.B73 | SENP5 peptidase |
hepatoma cell |
- |
753503 |
3.4.22.B75 | SENP7 peptidase |
hepatoma cell |
- |
752679 |
3.4.24.24 | gelatinase A |
hepatoma cell |
- |
683442 |
3.4.24.35 | gelatinase B |
hepatoma cell |
- |
701316 |
3.4.24.80 | membrane-type matrix metalloproteinase-1 |
hepatoma cell |
- |
681878 |
3.4.24.87 | ADAMTS13 endopeptidase |
hepatoma cell |
ADAMTS13 and von Willebrand factor contents, overview |
713533 |
3.4.99.B1 | RCE1 |
hepatoma cell |
- |
754247 |
3.5.1.6 | beta-ureidopropionase |
hepatoma cell |
- |
172058 |
3.5.2.2 | dihydropyrimidinase |
hepatoma cell |
- |
172058 |
3.5.3.1 | arginase |
hepatoma cell |
- |
696016 |
3.5.3.1 | arginase |
hepatoma cell |
arginase activity in hepatoma cell is nearly 5fold and 15fold lower than in cirrhotic and normal livers, respectively. The amount of arginase I, as well as the expression of arginase I-mRNA are lower in HCC, in comparison with normal liver, and those of arginase II are significantly higher |
696016 |
3.5.3.1 | arginase |
hepatoma cell |
arginase activity in hepatoma cell is nearly 5fold and 15fold lower than in cirrhotic and normal livers, respectively. The amount of arginase I, as well as the expression of arginase I-mRNA are lower in hepatoma cell, in comparison with normal liver, and those of arginase II are significantly higher |
696016 |
3.5.3.1 | arginase |
hepatoma cell |
HCC |
697070 |
3.5.3.15 | protein-arginine deiminase |
hepatoma cell |
strong expression |
666311 |
3.5.4.10 | IMP cyclohydrolase |
hepatoma cell |
- |
172163 |
3.5.4.6 | AMP deaminase |
hepatoma cell |
- |
700143 |
3.6.1.9 | nucleotide diphosphatase |
hepatoma cell |
- |
756172 |
3.9.1.3 | phosphohistidine phosphatase |
hepatoma cell |
in patients with hepatocellular carcinoma, low expression of LHPP correlated with increased tumour severity and reduced overall survival |
757801 |
4.1.1.17 | ornithine decarboxylase |
hepatoma cell |
- |
677508 |
4.1.1.32 | phosphoenolpyruvate carboxykinase (GTP) |
hepatoma cell |
- |
4365 |
4.1.1.32 | phosphoenolpyruvate carboxykinase (GTP) |
hepatoma cell |
Reuber H365 hepatoma cells |
4364 |
4.2.1.22 | cystathionine beta-synthase |
hepatoma cell |
- |
706024 |
4.2.1.22 | cystathionine beta-synthase |
hepatoma cell |
reduced cystathionine beta-synthase |
682533 |
4.2.1.3 | aconitate hydratase |
hepatoma cell |
- |
696168 |
4.3.1.4 | formimidoyltetrahydrofolate cyclodeaminase |
hepatoma cell |
- |
34325 |
4.3.1.4 | formimidoyltetrahydrofolate cyclodeaminase |
hepatoma cell |
HepG2 cell line |
34328 |
4.3.1.4 | formimidoyltetrahydrofolate cyclodeaminase |
hepatoma cell |
isoform of the formiminotransferase cyclodeaminase enzyme complex |
34325 |
4.3.2.1 | argininosuccinate lyase |
hepatoma cell |
- |
697084 |
5.2.1.8 | peptidylprolyl isomerase |
hepatoma cell |
- |
749058 |
6.1.1.19 | arginine-tRNA ligase |
hepatoma cell |
- |
672090 |
6.2.1.3 | long-chain-fatty-acid-CoA ligase |
hepatoma cell |
- |
662463, 673484, 674910 |
6.3.1.2 | glutamine synthetase |
hepatoma cell |
- |
676918 |
6.3.4.16 | carbamoyl-phosphate synthase (ammonia) |
hepatoma cell |
- |
672441, 672452, 673597 |
6.3.4.16 | carbamoyl-phosphate synthase (ammonia) |
hepatoma cell |
hepatoid tumors of gastric and yolk sac |
693935 |
6.3.4.3 | formate-tetrahydrofolate ligase |
hepatoma cell |
- |
765141 |
6.3.5.3 | phosphoribosylformylglycinamidine synthase |
hepatoma cell |
16, 20, 44, 7787, 7777, 3924A, 5123tc |
1664 |
6.3.5.4 | asparagine synthase (glutamine-hydrolysing) |
hepatoma cell |
- |
661295, 675566 |
7.2.2.9 | P-type Cu2+ transporter |
hepatoma cell |
Hep3B |
656023 |
7.6.2.4 | ABC-type fatty-acyl-CoA transporter |
hepatoma cell |
- |
667429 |