2.7.1.169: pantoate kinase
This is an abbreviated version!
For detailed information about pantoate kinase, go to the full flat file.
Word Map on EC 2.7.1.169
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2.7.1.169
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phosphopantothenate
-
thermococcus
-
kodakarensis
-
hyperthermophilic
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4'-phosphopantothenate
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pantothenate
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thermoplasmatales
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methanosarcina
-
mazei
-
picrophilus
-
utp
-
torridus
- 2.7.1.169
- phosphopantothenate
- thermococcus
- kodakarensis
-
hyperthermophilic
- 4'-phosphopantothenate
- pantothenate
- thermoplasmatales
-
methanosarcina
- mazei
-
picrophilus
- utp
- torridus
Reaction
Synonyms
COG1829, Mhun_0831, PoK, TK2141, TK2141 protein, TkPoK
ECTree
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Systematic Name
Systematic Name on EC 2.7.1.169 - pantoate kinase
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ATP:(R)-pantoate 4-phosphotransferase
The conversion of (R)-pantoate to (R)-4'-phosphopantothenate is part of the pathway leading to biosynthesis of 4'-phosphopantetheine, an essential cofactor of coenzyme A and acyl-carrier protein. In bacteria and eukaryotes this conversion is performed by condensation with beta-alanine, followed by phosphorylation (EC 6.3.2.1 and EC 2.7.1.33, respectively). In archaea the order of these two steps is reversed, and phosphorylation precedes condensation with beta-alanine.