2.7.1.169: pantoate kinase

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For detailed information about pantoate kinase, go to the full flat file.

Word Map on EC 2.7.1.169

2.7.1.169

phosphopantothenate

thermococcus

kodakarensis

hyperthermophilic

4'-phosphopantothenate

pantothenate

thermoplasmatales

methanosarcina

mazei

picrophilus

utp

torridus

Reaction

Synonyms

COG1829, Mhun_0831, PoK, TK2141, TK2141 protein, TkPoK

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.169 pantoate kinase

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Results	in table
2041	AA Sequence
2	Cloned(Commentary)
1	Cofactor
1	Crystallization (Commentary)
5	General Information
5	Inhibitors
7	kcat/KM [mM/s]
1	Ki Value [mM]
8	KM Value [mM]
11	Metals/Ions
2	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
6	Organism
5	Pathway
2	PDB ID
2	pH Optimum
1	pH Range
7	Protein Variants
1	Reaction
6	Reference
16	Substrates and Products (Substrate)
5	Subunits
15	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
8	Turnover Number [1/s]

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Cofactor on EC 2.7.1.169 - pantoate kinase

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ATP

Thermococcus kodakarensis

Q5JHF1

the electron density for the adenosine moiety of ATP is very weak, which most likely relates to its broad nucleotide specificity. The triphosphate moiety of ATP is surrounded by the lycine-rich loop of motif II (P96NGYGFGNSAG106). The magnesium ion can interact with oxygen atoms of beta- and gamma-phosphates, and with the O5' atom of ATP which bridges the adenosine and the triphosphate groups

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