2.6.1.86: 2-amino-4-deoxychorismate synthase
This is an abbreviated version!
For detailed information about 2-amino-4-deoxychorismate synthase, go to the full flat file.
Word Map on EC 2.6.1.86
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2.6.1.86
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anthranilate
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ammonia
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phenazine
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synthases
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amidotransferase
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enzyme-bound
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venezuelae
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aminodeoxychorismate
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chorismate-utilizing
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biotechnology
- 2.6.1.86
- anthranilate
- ammonia
- phenazine
- synthases
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amidotransferase
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enzyme-bound
- venezuelae
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aminodeoxychorismate
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chorismate-utilizing
- biotechnology
Reaction
Synonyms
2-amino-2-deoxyisochorismate (ADIC) synthase, 2-amino-2-deoxyisochorismate synthase, 2-amino-2desoxyisochorismate synthase, ADCS, ADIC synthase, aminodeoxyisochorismate synthase, PabA, PhzE, SgcD
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Natural Substrates Products
Natural Substrates Products on EC 2.6.1.86 - 2-amino-4-deoxychorismate synthase
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REACTION DIAGRAM
chorismate + L-glutamine
(2S)-2-amino-4-deoxychorismate + L-glutamate
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the net conversion of chorismate to 3-enolpyruvoylanthranilate by the tandem action of SgcD and SgcG establishes a new branching point in chorismate metabolism leading to synthesis of C-1027, an enediyne antitumor antibiotic
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additional information
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the enzyme participates in the biosynthesis of phenazine, a precursor for several compounds with antibiotic activity
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