2.4.1.224: glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase

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For detailed information about glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, go to the full flat file.

Word Map on EC 2.4.1.224

2.4.1.224

proteoglycans

exostoses

osteochondroma

glycosaminoglycans

glycosyltransferase

hedgehog

hspgs

chondrosarcoma

cartilaginous

syndecan-1

glypicans

cartilage-capped

wingless

perlecan

metaphyses

decapentaplegic

co-polymerase

medicine

Reaction

beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan

N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan

Synonyms

alpha-N-acetylglucosaminyltransferase II, exostosin-1, exostosin-2, Exostosin1, Exostosin2, EXT1, EXT2, extosin, glucuronyl-N-acetylglucosaminoproteoglycan 4-alpha-N-acetylglucosaminyltransferase, heparan sulfate polymerase, heparan sulfate synthesis enzyme, KfiA, More, N-acetyl-D-glucosaminyl-(N-acetyl-D-glucosamine) transferase, sister of tout velu, sister of tout-velu, sotv, tout-velu, ttv, UDP-GlcNAc:oligosaccharide beta-N-acetylglucosaminyltransferase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.224 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase

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Results	in table
1	Activating Compound
319	AA Sequence
1	Application
2	CAS Registry Number
16	Cloned(Commentary)
76	Disease/ Diagnostics
3	Expression
32	General Information
1	General Stability
8	KM Value [mM]
23	Localization
2	Metals/Ions
15	Molecular Weight [Da]
24	Natural Substrates/ Products (Substrates)
253	Organism
3	Pathway
10	PDB ID
1	pH Optimum
2	pH Range
3	pI Value
8	Posttranslational Modification
23	Protein Variants
5	Purification (Commentary)
1	Reaction
1	Reaction Type
51	Reference
38	Source Tissue
1	Specific Activity [micromol/min/mg]
78	Substrates and Products (Substrate)
6	Subunits
58	Synonyms
1	Systematic Name

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Natural Substrates Products on EC 2.4.1.224 - glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase

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UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan

UDP + N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan

10 entries

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2 entries