2.3.3.18: 2-phosphinomethylmalate synthase

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For detailed information about 2-phosphinomethylmalate synthase, go to the full flat file.

Reaction

Synonyms

2-phosphinomethylmalic acid synthase, pmmS

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.3 Acyl groups converted into alkyl groups on transfer

                2.3.3.18 2-phosphinomethylmalate synthase

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Results	in table
2	Activating Compound
1	AA Sequence
13	Inhibitors
5	KM Value [mM]
2	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
8	Organism
4	Pathway
1	pH Optimum
1	Purification (Commentary)
1	Reaction
4	Reference
1	Specific Activity [micromol/min/mg]
1	Storage Stability
8	Substrates and Products (Substrate)
2	Subunits
5	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 2.3.3.18 - 2-phosphinomethylmalate synthase

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SYSTEMATIC NAME

IUBMB Comments

acetyl-CoA:phosphinopyruvate C-acetyltransferase (thioester-hydrolysing, phosphinomethylmalate-forming)

The enzyme, characterized from the bacterium Streptomyces hygroscopicus, participates in the pathway for bialaphos biosynthesis. It requires a divalent metal ion and can also act on oxaloacetate.