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2.1.1.321: type III protein arginine methyltransferase

This is an abbreviated version!
For detailed information about type III protein arginine methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.321

Reaction

S-adenosyl-L-methionine
+
[protein]-L-arginine
=
S-adenosyl-L-homocysteine
+
[protein]-Nomega-methyl-L-arginine

Synonyms

EC 2.1.1.124, EC 2.1.1.125, EC 2.1.1.126, EC 2.1.1.23, PRMT-7, PRMT7, protein arginine methyltransferase 7

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.321 type III protein arginine methyltransferase

Inhibitors

Inhibitors on EC 2.1.1.321 - type III protein arginine methyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
adenosine dialdehyde
blocks the action of PRMT7 in ccRCC cells
NaCl
sodium chloride strongly inhibits the activity of the human enzyme. Half maximal activity is seen at about 25 mM with a peptide substrate based on histone H2B and about 200 mM for the GST-GAR protein substrate