EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.5.1.3 | Acquired Immunodeficiency Syndrome |
1402679 |
Application of DNA amplification to pneumocystosis: presence of serum Pneumocystis carinii DNA during human and experimentally induced Pneumocystis carinii pneumonia. |
causal interaction
diagnostic usage
unassigned |
3
2
0 |
| 1.5.1.3 | Acquired Immunodeficiency Syndrome |
2353761 |
[Acute pancytopenia induced by pyrimethamine during treatment of cerebral toxoplasmosis associated with AIDS. Role of dihydrofolate reductase inhibitors] |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 1.5.1.3 | Acquired Immunodeficiency Syndrome |
7594732 |
Diagnosis of Pneumocystis carinii pneumonia in AIDS patients by using polymerase chain reactions on serum specimens. |
diagnostic usage
unassigned |
4
0 |
| 1.5.1.3 | Acquired Immunodeficiency Syndrome |
8230096 |
2,4-Diaminothieno[2,3-d]pyrimidine analogues of trimetrexate and piritrexim as potential inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase. |
causal interaction
therapeutic application
unassigned |
2
3
0 |
| 1.5.1.3 | Acquired Immunodeficiency Syndrome |
8454599 |
Primary structure of the dihydrofolate reductase-thymidylate synthase gene from Toxoplasma gondii. |
causal interaction
unassigned |
1
0 |
| 1.5.1.3 | Acquired Immunodeficiency Syndrome |
8501335 |
Salvage trial of trimetrexate-leucovorin for the treatment of cerebral toxoplasmosis in patients with AIDS. |
diagnostic usage
therapeutic application
unassigned |
3
2
0 |
| 1.5.1.3 | Acquired Immunodeficiency Syndrome |
8855552 |
Potential antifolate resistance determinants and genotypic variation in the bifunctional dihydrofolate reductase-thymidylate synthase gene from human and bovine isolates of Cryptosporidium parvum. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
4
4
0 |
| 1.5.1.3 | Acquired Immunodeficiency Syndrome |
9046337 |
Synthesis and dihydrofolate reductase inhibitory activities of 2,4-diamino-5-deaza and 2,4-diamino-5,10-dideaza lipophilic antifolates. |
therapeutic application
unassigned |
2
0 |
| 1.5.1.3 | Acquired Immunodeficiency Syndrome |
9301665 |
Conformationally restricted analogues of trimethoprim: 2,6-diamino-8-substituted purines as potential dihydrofolate reductase inhibitors from Pneumocystis carinii and Toxoplasma gondii. |
unassigned |
0 |
| 1.5.1.3 | Acquired Immunodeficiency Syndrome |
9804692 |
6-Substituted 2,4-diaminopyrido[3,2-d]pyrimidine analogues of piritrexim as inhibitors of dihydrofolate reductase from rat liver, Pneumocystis carinii, and Toxoplasma gondii and as antitumor agents. |
ongoing research
unassigned |
1
0 |
