EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.14.19.28 | Carcinogenesis |
26856390 |
DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by down-regulating the EGFR/AKT pathway in esophageal squamous cell carcinoma. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
3
2
0 |
| 1.14.19.28 | Carcinoma |
11161383 |
Differential expression of a novel serine protease homologue in squamous cell carcinoma of the head and neck. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
3
3
0 |
| 1.14.19.28 | Carcinoma |
16320362 |
Expression of the serine protease DESC1 correlates directly with normal keratinocyte differentiation and inversely with head and neck squamous cell carcinoma progression. |
causal interaction
diagnostic usage
unassigned |
4
3
0 |
| 1.14.19.28 | Carcinoma |
17388811 |
Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
3
0 |
| 1.14.19.28 | Carcinoma |
17579619 |
Human DESC1 serine protease confers tumorigenic properties to MDCK cells and it is upregulated in tumours of different origin. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
2
3
4 |
| 1.14.19.28 | Carcinoma |
26856390 |
DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by down-regulating the EGFR/AKT pathway in esophageal squamous cell carcinoma. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
3
2
0 |
| 1.14.19.28 | Carcinoma |
29530057 |
LncRNA-TUSC7/miR-224 affected chemotherapy resistance of esophageal squamous cell carcinoma by competitively regulating DESC1. |
therapeutic application
unassigned |
3
0 |
| 1.14.19.28 | Carcinoma |
33391449 |
LncRNA LOXL1-AS1 promotes esophageal squamous cell carcinoma progression by targeting DESC1. |
unassigned |
0 |
| 1.14.19.28 | Carcinoma, Squamous Cell |
11161383 |
Differential expression of a novel serine protease homologue in squamous cell carcinoma of the head and neck. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
3
3
0 |
| 1.14.19.28 | Carcinoma, Squamous Cell |
16320362 |
Expression of the serine protease DESC1 correlates directly with normal keratinocyte differentiation and inversely with head and neck squamous cell carcinoma progression. |
causal interaction
diagnostic usage
unassigned |
4
3
0 |
