EC Number   |
|---|
    1.8.1.12 | - |
| 1.8.1.12 | crystal structure of thr enzyme (LiTR) at 3.6 A resolution in its reduced state (complex with trypanothione) and oxidized state |
| 1.8.1.12 | hanging drop method in presence of 2 M (NH4)2SO4 at 4°C |
| 1.8.1.12 | hanging drop vapor diffusion method |
| 1.8.1.12 | hanging drop vapor diffusion method, using 0.1 M bis-Tris propane pH 8.0, 5% (v/v) PEG 400, 2M ammonium sulfate |
| 1.8.1.12 | hanging drop vapour diffusion method, using ammonium sulfate as precipitant agent, at 21°C |
| 1.8.1.12 | identification of putative inhibitors by molecular docking |
| 1.8.1.12 | in complex with inhibitor 6-(sec-butoxy)-2-((3-chlorophenyl)thio)pyrimidin-4-amine. The inhibitor binds to the catalytic site and interacts with residues Glu466', Cys57 and Cys52 |
| 1.8.1.12 | molecular docking of 5-nitroimidazole analogues to identify putative inhibitors |
| 1.8.1.12 | molecular docking of inhibitor isopropyl 2-isobutyryl-3-trifluoromethylquinoxaline-7-carboxylate 1,4-di-N-oxide |
