EC Number |
Turnover Number Minimum [1/s] |
Turnover Number Maximum [1/s] |
Substrate |
Reference |
---|
1.1.1.146 | 0.0000883 |
- |
11beta,21-dihydroxypregn-4-en-3,20-dione |
at pH 7.0 |
285962 |
1.1.1.146 | 0.000113 |
- |
21-hydroxy-pregn-4-en-3,11,20-trione |
at pH 7.0 |
285962 |
1.1.1.146 | 0.000183 |
- |
21-hydroxy-pregn-4-en-3,11,20-trione |
at pH 8.5 |
285962 |
1.1.1.146 | 0.000228 |
- |
11beta,21-dihydroxypregn-4-en-3,20-dione |
at pH 8.5 |
285962 |
1.1.1.146 | 0.04 |
- |
cortisol |
37°C, pH 7.4, recombinant 11beta-HSD1 expressed in Escherichia coli |
656133 |
1.1.1.146 | 0.042 |
- |
cortisol |
pH 7.5, 22°C, recombinant wild-type isozyme 11beta-HSD1 |
669419 |
1.1.1.146 | 0.078 |
- |
cortisol |
pH 7.5, 22°C, recombinant wild-type isozyme 11beta-HSD1 oxidized with K3Fe(CN)6 |
669419 |
1.1.1.146 | 0.19 |
- |
cortisol |
37°C, pH 7.4, recombinant 11beta-HSD1 expressed in Escherichia coli |
656133 |
1.1.1.146 | 0.3 |
- |
cortisone |
37°C, pH 7.4, recombinant 11beta-HSD1 expressed in Escherichia coli |
656133 |
1.1.1.146 | 0.4 |
- |
cortisone |
37°C, pH 7.4, recombinant 11beta-HSD1 expressed in Escherichia coli |
656133 |