EC Number   |
Specific Activity Minimum [µmol/min/mg] |
Specific Activity Maximum [µmol/min/mg] |
Reference |
|---|
    2.5.1.61 | -999 |
- |
- |
489921, 489922, 489923, 489925, 489933, 489934, 489937, 489942, 489944, 489949, 489952, 489953, 5883 |
| 2.5.1.61 | -999 |
- |
activity determinatin by uroporphyrinogen formation measurement |
737881 |
| 2.5.1.61 | -999 |
- |
activity of recombinant wild-type and mutant enzymes in transfected SH-SY5Y neuroblastoma cells, overview |
672383 |
| 2.5.1.61 | -999 |
- |
cf1 mutant tissue shows 30% reduced activity (about 0.7 units/mg) compared to wild type (about 2.5 units/mg) in green and yellow leaf tissue, consistent with reduced enzyme abundance, 13fold substrate accumulation |
710016 |
| 2.5.1.61 | -999 |
- |
enzyme activity in lymphoblasts from variegate porphyria subjects |
489948 |
| 2.5.1.61 | -999 |
- |
enzyme activity is sharply dependent on pH |
489941 |
| 2.5.1.61 | -999 |
- |
enzyme activity is temperature-dependent |
489926 |
| 2.5.1.61 | -999 |
- |
erythrocyte enzyme activity in acute intermittent porphyria mice (7.3 pM uroporphyrin/mg hemoglobin) does not improve with bone marrow graft from porphyria mice (5.2 pM uroporphyrin/mg hemoglobin), increases to 12.4 pM uroporphyrin/mg hemoglobin in mice grafted with bone marrow from wild type, wild type has an activity of 16.9 pM uroporphyrin/mg hemoglobin, erythrocyte enzyme deficiency is not associated with acute porphyria, 37°C, phosphate buffered saline |
709334 |
| 2.5.1.61 | -999 |
- |
hepatic enzyme activity in untreated acute intermittent porphyria mice (2.2 pM uroporphyrin/mg hemoglobin) does not increase with control plasmid (2.1 pM uroporphyrin/mg hemoglobin) but increases upon treatment with a therapeutic plasmid containing the human wild type enzyme (4.7 pM uroporphyrin/mg hemoglobin), the wild type shows 10 pM uroporphyrin/mg hemoglobin activity, hepatic enzyme deficiency is associated with acute porphyria, 37°C, phosphate buffered saline |
709334 |
| 2.5.1.61 | -999 |
- |
linked assay with HemB, CobA/HemD enzymes in 50 mM Tris-HCl, pH 8.0, 2 hours at 25°C produces precorrin-2 from the substrate aminolaevulinic acid |
696120 |
