EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
5.3.99.5 | thromboxane-A synthase |
HL-60 cell |
low activity |
3183 |
5.6.2.2 | DNA topoisomerase (ATP-hydrolysing) |
HL-60 cell |
- |
3884, 678594, 681905, 691220, 691488, 691529, 693548, 695190, 702602, 702620, 714427, 714900, 715842, 716887, 727301, 750475 |
2.3.1.149 | Platelet-activating factor acetyltransferase |
HL-60 cell |
- |
16279 |
3.4.21.76 | Myeloblastin |
HL-60 cell |
- |
29718, 710661 |
3.1.3.25 | inositol-phosphate phosphatase |
HL-60 cell |
- |
114225 |
3.1.4.12 | sphingomyelin phosphodiesterase |
HL-60 cell |
- |
135176, 135180, 135187, 678375 |
3.1.4.4 | phospholipase D |
HL-60 cell |
human leucemia cell line |
135440 |
3.4.25.1 | proteasome endopeptidase complex |
HL-60 cell |
- |
137358, 685565, 733663 |
3.1.4.1 | phosphodiesterase I |
HL-60 cell |
- |
208356 |
7.6.2.2 | ABC-type xenobiotic transporter |
HL-60 cell |
- |
210395, 210399, 210400, 210401, 710872 |
7.6.2.2 | ABC-type xenobiotic transporter |
HL-60 cell |
MRP-overexpressing HL60/ADR cells |
210402 |
3.1.1.77 | acyloxyacyl hydrolase |
HL-60 cell |
- |
246545, 246546, 246547, 246548, 246549, 246550 |
1.1.1.205 | IMP dehydrogenase |
HL-60 cell |
leukemic cell line |
347916 |
2.3.1.125 | 1-alkyl-2-acetylglycerol O-acyltransferase |
HL-60 cell |
- |
486246 |
2.3.1.20 | diacylglycerol O-acyltransferase |
HL-60 cell |
leukemia, HL-60 cell line |
486246 |
2.3.1.67 | 1-alkylglycerophosphocholine O-acetyltransferase |
HL-60 cell |
differentiated |
487375 |
2.4.1.80 | ceramide glucosyltransferase |
HL-60 cell |
- |
489417, 691791 |
2.7.11.15 | beta-adrenergic-receptor kinase |
HL-60 cell |
high expression of beta-ARK 1 |
490989 |
2.7.11.13 | protein kinase C |
HL-60 cell |
- |
491032 |
2.4.1.150 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase |
HL-60 cell |
C2GnT, promyelocytic leukaemia HL-60 cells |
638564 |
2.4.1.152 | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase |
HL-60 cell |
- |
639528 |
2.7.1.107 | diacylglycerol kinase (ATP) |
HL-60 cell |
level of DGKgamma is rapidly and markedly decreased upon cellular differentiation into macrophages |
640373 |
2.7.1.107 | diacylglycerol kinase (ATP) |
HL-60 cell |
levels of DGKgamma mRNA/protein is rapidly and markedly decreased upon cellular differentiation into macrophages |
640373 |
2.7.1.127 | inositol-trisphosphate 3-kinase |
HL-60 cell |
non-differentiated promyelocytic-leukaemia cell line, InsP3 3-kinase B mRNA |
640751 |
2.7.1.60 | N-acylmannosamine kinase |
HL-60 cell |
- |
641741 |
4.4.1.20 | leukotriene-C4 synthase |
HL-60 cell |
monocytic leukemia cell line |
644492 |
3.4.19.9 | folate gamma-glutamyl hydrolase |
HL-60 cell |
- |
647319 |
3.4.22.56 | caspase-3 |
HL-60 cell |
promyelocytic cell |
647607 |
6.3.4.2 | CTP synthase (glutamine hydrolysing) |
HL-60 cell |
- |
648969 |
6.1.1.20 | phenylalanine-tRNA ligase |
HL-60 cell |
promyelocytic leukemia cell line, high content |
649540 |
3.1.1.47 | 1-alkyl-2-acetylglycerophosphocholine esterase |
HL-60 cell |
- |
650326 |
3.4.24.B7 | matrix metalloproteinase-26 |
HL-60 cell |
promyelocytic leukemia, gene expression |
650768 |
3.1.4.11 | phosphoinositide phospholipase C |
HL-60 cell |
promyelocytic cell line, undifferentiated and DMSO-differentiated |
650786 |
3.4.21.108 | HtrA2 peptidase |
HL-60 cell |
- |
652027 |
3.5.1.88 | peptide deformylase |
HL-60 cell |
- |
654445 |
1.3.1.72 | DELTA24-sterol reductase |
HL-60 cell |
promyelocytic cells |
654502 |
3.2.2.5 | NAD+ glycohydrolase |
HL-60 cell |
leukemic cells, retinoic acid-treated |
654609 |
3.2.1.51 | alpha-L-fucosidase |
HL-60 cell |
- |
655418 |
1.4.3.5 | pyridoxal 5'-phosphate synthase |
HL-60 cell |
2.3% of the activity in liver |
655483 |
3.6.1.13 | ADP-ribose diphosphatase |
HL-60 cell |
- |
655991 |
2.1.1.6 | catechol O-methyltransferase |
HL-60 cell |
- |
657534 |
2.5.1.6 | methionine adenosyltransferase |
HL-60 cell |
leukemia promyelotic cells |
657534 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
HL-60 cell |
- |
657703 |
1.14.14.94 | leukotriene-B4 20-monooxygenase |
HL-60 cell |
induction of in all-trans-retinoic acid-treated HL60 cells |
657762 |
1.8.1.7 | glutathione-disulfide reductase |
HL-60 cell |
doxorubicin-insensitive leukemic cell line HL-60-R, a subclone of HL-60 |
657878 |
2.4.1.143 | alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
HL-60 cell |
- |
658123 |
2.4.1.144 | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
HL-60 cell |
- |
658123 |
2.4.1.155 | alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase |
HL-60 cell |
- |
658123 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
HL-60 cell |
phorbol myristate actetate-stimulated |
658140 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
HL-60 cell |
the cAMP responsive element binding protein binding site of the hST3Gal V promoter plays a critical role in transcriptional regulation of the hST3Gal V gene during HL-60 cell differentiation |
658723 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
HL-60 cell |
upregulation of GM3 synthase through protein kinase C/extracellular regulated kinases-dependent cAMP-responsive element binding protein activation results in the differentiation of HL-60 cells by inducing expression of CD11b |
658853 |
1.7.1.7 | GMP reductase |
HL-60 cell |
- |
659550 |
2.7.4.21 | inositol-hexakisphosphate 5-kinase |
HL-60 cell |
- |
662355 |
2.7.1.74 | deoxycytidine kinase |
HL-60 cell |
- |
662521, 721969, 761020 |
2.7.10.2 | non-specific protein-tyrosine kinase |
HL-60 cell |
promyelotic leukemia cell line |
662838 |
5.6.2.2 | DNA topoisomerase (ATP-hydrolysing) |
HL-60 cell |
vincristine-resistant leukemia cell line |
662920 |
3.5.3.15 | protein-arginine deiminase |
HL-60 cell |
- |
664107, 733099 |
3.2.1.143 | poly(ADP-ribose) glycohydrolase |
HL-60 cell |
promyelocytic leukemia cell line |
664169 |
4.1.1.17 | ornithine decarboxylase |
HL-60 cell |
human acute myeloid leukemia cell, enzyme activity correlates with myeloid cell differentiation induced by retinoic acid treatment |
664295 |
3.1.4.4 | phospholipase D |
HL-60 cell |
- |
664880, 708460 |
3.1.6.2 | steryl-sulfatase |
HL-60 cell |
acute myeloid leukaemia cell line |
665806 |
3.1.2.4 | 3-hydroxyisobutyryl-CoA hydrolase |
HL-60 cell |
promyelocytic leukemia cell line |
665823 |
3.1.4.4 | phospholipase D |
HL-60 cell |
the expression pattern of PLD1 and PLD2 mRNA isoforms induced to differentiate varies with DSMO and all-trans retinoic acid |
665957 |
3.1.4.4 | phospholipase D |
HL-60 cell |
the expression pattern of PLD1 and PLD2 mRNA isoforms induced to differentiate varies with DSMO and ATRA |
665957 |
3.4.11.6 | aminopeptidase B |
HL-60 cell |
neutrophilic promyelocyte cell line |
666799 |
3.1.4.11 | phosphoinositide phospholipase C |
HL-60 cell |
phosphorylation of nuclear PLC-beta1b on serine occurs at the G2/M and the late G1 phase and is necessary for the progression of the cells through the cell cycle |
667801 |
3.1.4.11 | phosphoinositide phospholipase C |
HL-60 cell |
isoenzyme PI-PLC-ß1 |
668867 |
3.4.17.1 | carboxypeptidase A |
HL-60 cell |
low expression level |
669629 |
5.6.1.3 | plus-end-directed kinesin ATPase |
HL-60 cell |
- |
670955 |
2.5.1.39 | 4-hydroxybenzoate polyprenyltransferase |
HL-60 cell |
- |
671299 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
HL-60 cell |
- |
671713 |
2.7.1.113 | deoxyguanosine kinase |
HL-60 cell |
- |
671801 |
2.7.1.113 | deoxyguanosine kinase |
HL-60 cell |
3fold increase when cells start to proliferate |
671801 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
HL-60 cell |
type 2 isozyme |
672358 |
2.7.10.2 | non-specific protein-tyrosine kinase |
HL-60 cell |
macrophage-like differentiated |
672781 |
1.17.4.2 | ribonucleoside-triphosphate reductase (thioredoxin) |
HL-60 cell |
promyelocytic leukemia cells |
672890 |
2.4.2.8 | hypoxanthine phosphoribosyltransferase |
HL-60 cell |
myeloid leukemic cell line |
672965 |
2.1.1.355 | [histone H3]-lysine9 N-trimethyltransferase |
HL-60 cell |
interaction between growth factor independent 1 and G9a in vivo |
675958 |
2.7.11.15 | beta-adrenergic-receptor kinase |
HL-60 cell |
- |
677232 |
4.1.1.17 | ornithine decarboxylase |
HL-60 cell |
- |
677616, 699928, 699929, 699934 |
5.6.2.2 | DNA topoisomerase (ATP-hydrolysing) |
HL-60 cell |
sensitive to topoisomerase II inhibitors |
678097 |
3.1.4.11 | phosphoinositide phospholipase C |
HL-60 cell |
- |
678438, 679976, 682863 |
2.7.12.2 | mitogen-activated protein kinase kinase |
HL-60 cell |
- |
679032, 740713 |
6.3.4.21 | nicotinate phosphoribosyltransferase |
HL-60 cell |
- |
680797 |
3.2.1.24 | alpha-mannosidase |
HL-60 cell |
human promyelocytic leukemia HL-60 cells |
681902 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
HL-60 cell |
- |
682531 |
1.14.19.20 | DELTA7-sterol 5(6)-desaturase |
HL-60 cell |
- |
682873 |
1.3.1.72 | DELTA24-sterol reductase |
HL-60 cell |
- |
682873, 764619 |
3.4.21.78 | granzyme A |
HL-60 cell |
no expression of granzyme A in promyelocytic cell line HL-60 identified |
683529 |
3.4.24.24 | gelatinase A |
HL-60 cell |
leukemia cell line, secretion of MMP-2 |
683579 |
3.4.24.35 | gelatinase B |
HL-60 cell |
leukemia cell line, secretion of MMP-9 |
683579 |
2.1.1.13 | methionine synthase |
HL-60 cell |
- |
684467, 733653 |
2.5.1.49 | O-acetylhomoserine aminocarboxypropyltransferase |
HL-60 cell |
- |
684467 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
HL-60 cell |
- |
685998, 711166, 763912 |
3.4.21.76 | Myeloblastin |
HL-60 cell |
cell associated PR3 levels are lower than in neutrophils, thus sensitivity of the indirect immunofluorescence test is lower |
686188 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
HL-60 cell |
bilirubin concentration-dependently reduces NADPH oxidase-dependent superoxide production stimulated by phorbol 12-myristate 13-acetate |
687050 |
1.17.4.2 | ribonucleoside-triphosphate reductase (thioredoxin) |
HL-60 cell |
- |
687180 |
7.6.2.1 | P-type phospholipid transporter |
HL-60 cell |
promyelocytic leukemia cells |
687676 |
1.17.4.1 | ribonucleoside-diphosphate reductase |
HL-60 cell |
a promyelocytic leukemia cell line |
688283 |
1.8.1.9 | thioredoxin-disulfide reductase |
HL-60 cell |
- |
688735 |