EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
2.7.1.20 | adenosine kinase |
astrocyte |
astrocyte-based ADK provides a critical link between astrogliosis and neuronal dysfunction in epilepsy |
687973 |
2.7.1.20 | adenosine kinase |
astrocyte |
expressed most strongly in astrocytes |
676193 |
2.7.1.59 | N-acetylglucosamine kinase |
astrocyte |
low expression |
739070 |
2.7.10.1 | receptor protein-tyrosine kinase |
astrocyte |
- |
490550 |
2.7.11.10 | IkappaB kinase |
astrocyte |
- |
694136 |
2.7.11.13 | protein kinase C |
astrocyte |
- |
693314, 725768 |
2.7.11.13 | protein kinase C |
astrocyte |
primary, cortical |
661460 |
2.7.11.2 | [pyruvate dehydrogenase (acetyl-transferring)] kinase |
astrocyte |
- |
761984 |
2.7.11.24 | mitogen-activated protein kinase |
astrocyte |
- |
697804, 702065 |
2.7.11.25 | mitogen-activated protein kinase kinase kinase |
astrocyte |
- |
742223 |
2.7.3.2 | creatine kinase |
astrocyte |
- |
737427, 761135 |
2.7.7.15 | choline-phosphate cytidylyltransferase |
astrocyte |
- |
-, 721714 |
2.7.7.83 | UDP-N-acetylgalactosamine diphosphorylase |
astrocyte |
- |
722110 |
2.8.1.2 | 3-mercaptopyruvate sulfurtransferase |
astrocyte |
- |
739470 |
2.8.2.17 | chondroitin 6-sulfotransferase |
astrocyte |
- |
738897 |
3.1.1.23 | acylglycerol lipase |
astrocyte |
primary |
666129 |
3.1.1.4 | phospholipase A2 |
astrocyte |
- |
653367 |
3.1.3.21 | glycerol-1-phosphatase |
astrocyte |
- |
681523 |
3.1.3.3 | phosphoserine phosphatase |
astrocyte |
- |
682867 |
3.1.3.5 | 5'-nucleotidase |
astrocyte |
- |
-, 715987, 750661 |
3.1.3.67 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase |
astrocyte |
primary astrocyte, expression of wild-type enzyme |
650911 |
3.1.3.74 | pyridoxal phosphatase |
astrocyte |
- |
-, 715124 |
3.1.3.74 | pyridoxal phosphatase |
astrocyte |
4-5 days after ischemia PLP-P expressed in glial components |
679694 |
3.1.3.9 | glucose-6-phosphatase |
astrocyte |
- |
750367 |
3.1.3.9 | glucose-6-phosphatase |
astrocyte |
low enzyme activities |
649729 |
3.1.3.9 | glucose-6-phosphatase |
astrocyte |
primary |
665603 |
3.1.4.11 | phosphoinositide phospholipase C |
astrocyte |
- |
681021, 682552, 715713 |
3.1.4.11 | phosphoinositide phospholipase C |
astrocyte |
adult brain, PLC-delta1 is concentrated in astroglial cells, much lower levels in neurons |
653442 |
3.1.4.11 | phosphoinositide phospholipase C |
astrocyte |
PI-PLC delta3 |
681021 |
3.1.4.11 | phosphoinositide phospholipase C |
astrocyte |
PLC-gamma1 mRNA is widely detected in various tissues. It is abundantly expressed in embryonal cortical structures, neurons, oligodendrocytes and astrocytes |
691473 |
3.1.4.12 | sphingomyelin phosphodiesterase |
astrocyte |
- |
692073 |
3.1.4.12 | sphingomyelin phosphodiesterase |
astrocyte |
cortical astrocyte, acid SMase |
716445 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
astrocyte |
- |
652975 |
3.1.4.4 | phospholipase D |
astrocyte |
- |
708012 |
3.1.4.4 | phospholipase D |
astrocyte |
primary |
710112 |
3.1.6.12 | N-acetylgalactosamine-4-sulfatase |
astrocyte |
- |
729806 |
3.2.1.143 | poly(ADP-ribose) glycohydrolase |
astrocyte |
cell culture |
666771 |
3.2.1.143 | poly(ADP-ribose) glycohydrolase |
astrocyte |
cortical cell culture |
700897 |
3.2.1.143 | poly(ADP-ribose) glycohydrolase |
astrocyte |
primary culture |
664476 |
3.2.2.6 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase |
astrocyte |
- |
731882 |
3.3.2.10 | soluble epoxide hydrolase |
astrocyte |
- |
-, 699685, 710118, 731562, 753120 |
3.3.2.10 | soluble epoxide hydrolase |
astrocyte |
cortical and hippocampal |
707927 |
3.3.2.10 | soluble epoxide hydrolase |
astrocyte |
scattered astrocyte |
683721 |
3.3.2.9 | microsomal epoxide hydrolase |
astrocyte |
- |
699680, 699685, 710118, 753726 |
3.3.2.9 | microsomal epoxide hydrolase |
astrocyte |
patchy distribution |
661658 |
3.4.11.2 | membrane alanyl aminopeptidase |
astrocyte |
- |
665112 |
3.4.11.3 | cystinyl aminopeptidase |
astrocyte |
- |
753121 |
3.4.14.9 | tripeptidyl-peptidase I |
astrocyte |
- |
697808 |
3.4.17.10 | carboxypeptidase E |
astrocyte |
cell culture |
669606 |
3.4.17.21 | Glutamate carboxypeptidase II |
astrocyte |
- |
669923, 669962, 670363, 670397, 701258, 731257, 752980 |
3.4.17.21 | Glutamate carboxypeptidase II |
astrocyte |
the level of glutamate carboxypeptidase II protein (GCPII) is regulated by valproic acid, a histone deacetylase (HDAC) inhibitor, through acetylation of lysine residue in the GCPII protein in human astrocytes, U-87MG |
752648 |
3.4.17.23 | angiotensin-converting enzyme 2 |
astrocyte |
transcriptional regulation of ACE2 mRNA in astrocytes is dependent on the relative concentrations of both angiotensin II and angiotensin(17) as well as on interaction with their respective receptors |
-, 667146 |
3.4.18.1 | cathepsin X |
astrocyte |
- |
683448 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
astrocyte |
- |
710451 |
3.4.21.109 | matriptase |
astrocyte |
- |
717799 |
3.4.21.68 | t-Plasminogen activator |
astrocyte |
- |
-, 718266, 718403 |
3.4.21.7 | plasmin |
astrocyte |
plasmin evokes an increase in both phosphoinositide hydrolysis and Fura-2/AM fluorescence in cultured cortical astrocytes. Plasmin activiates extracellular signal-regulated kinase and induces a rise in intracellular Ca2+ concentration and phopho-ERK1/2 levels |
698776 |
3.4.21.75 | Furin |
astrocyte |
primary cortical |
-, 732368 |
3.4.21.B10 | neurosin |
astrocyte |
primary cell culture |
731396 |
3.4.21.B7 | mannan-binding lectin-associated serine protease 1 |
astrocyte |
- |
666927 |
3.4.22.1 | cathepsin B |
astrocyte |
- |
707002 |
3.4.22.27 | cathepsin S |
astrocyte |
- |
696995 |
3.4.22.36 | caspase-1 |
astrocyte |
- |
681931 |
3.4.22.56 | caspase-3 |
astrocyte |
primary |
700938 |
3.4.22.60 | caspase-7 |
astrocyte |
primary |
700938 |
3.4.22.61 | caspase-8 |
astrocyte |
- |
697771, 710108 |
3.4.22.61 | caspase-8 |
astrocyte |
no change in activity after irradiation |
664508 |
3.4.22.64 | caspase-11 |
astrocyte |
- |
664925, 708506, 709623 |
3.4.22.B25 | calpain 5 |
astrocyte |
- |
-, 732139 |
3.4.22.B72 | SENP3 peptidase |
astrocyte |
- |
-, 731627, 731628 |
3.4.23.45 | memapsin 1 |
astrocyte |
- |
754574 |
3.4.23.46 | memapsin 2 |
astrocyte |
astrocytic BACE1 expression may be important to the development of pathology in Alzheimer's disease |
669930 |
3.4.23.5 | cathepsin D |
astrocyte |
- |
711354, 713109, 753898 |
3.4.24.16 | neurolysin |
astrocyte |
- |
37080, 37082 |
3.4.24.16 | neurolysin |
astrocyte |
contain only soluble enzyme |
37076 |
3.4.24.35 | gelatinase B |
astrocyte |
- |
710106, 734590 |
3.4.24.35 | gelatinase B |
astrocyte |
enzyme expression is slightly induced by HIV and strongly induced by TNF alpha, while matrix metalloproteinase MMP-2 and tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 are only slightly affected. Astrocytes are a major source of enzyme in the inflamed brain |
670149 |
3.4.24.35 | gelatinase B |
astrocyte |
secretion, induced by interleukin-1beta |
683874 |
3.4.24.56 | insulysin |
astrocyte |
primary |
683801 |
3.4.24.71 | endothelin-converting enzyme 1 |
astrocyte |
- |
684002 |
3.4.24.71 | endothelin-converting enzyme 1 |
astrocyte |
lower expression of ECE-1 |
710094 |
3.4.24.81 | ADAM10 endopeptidase |
astrocyte |
strain U373 MG |
669957 |
3.4.24.82 | ADAMTS-4 endopeptidase |
astrocyte |
- |
668117 |
3.4.24.82 | ADAMTS-4 endopeptidase |
astrocyte |
cell culture, expression of aggrecanase-1 mRNA is induced if cells are treated with beta-amyloid |
638959 |
3.4.24.86 | ADAM 17 endopeptidase |
astrocyte |
- |
639002 |
3.4.24.87 | ADAMTS13 endopeptidase |
astrocyte |
in cerebral corpora amylacea, that occur in aging brains and in patients with neurodegenerative conditions |
713116 |
3.4.24.B10 | ADAM12 endopeptidase |
astrocyte |
- |
711642 |
3.4.24.B11 | ADAMTS1 endopeptidase |
astrocyte |
- |
668117 |
3.4.24.B18 | m-AAA protease |
astrocyte |
- |
753753 |
3.4.24.B4 | matrix metalloproteinase-13 |
astrocyte |
MMP-13 is mainly produced by neurons, but also by astrocytes |
693332 |
3.4.24.B4 | matrix metalloproteinase-13 |
astrocyte |
primary |
712559 |
3.4.24.B7 | matrix metalloproteinase-26 |
astrocyte |
astrocytic gliom tissue |
754946 |
3.4.25.1 | proteasome endopeptidase complex |
astrocyte |
- |
711354 |
3.4.25.1 | proteasome endopeptidase complex |
astrocyte |
differentiated from C6 glioma cells |
-, 720289 |
3.4.25.1 | proteasome endopeptidase complex |
astrocyte |
from subjects with Alexander disease |
712414 |
3.5.1.2 | glutaminase |
astrocyte |
isozymes LGA and KGA |
670391 |
3.5.1.2 | glutaminase |
astrocyte |
phosphate-activated isozyme |
670129 |
3.5.1.3 | omega-amidase |
astrocyte |
omega-amidase activity is about the same in cultured chick astrocytes and neurons |
288890 |
3.5.1.3 | omega-amidase |
astrocyte |
omega-amidase activity is higher in astrocytes than in neurons |
288890 |
3.5.1.3 | omega-amidase |
astrocyte |
omega-amidase activity is significantly higher in astrocytes than in neurons |
288890 |