1.1.1.149 20alpha-hydroxysteroid dehydrogenase astrocyte - 763094 1.1.1.21 aldose reductase astrocyte - -, 739113 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) astrocyte high expression and activity in astrocytes of glaucomatous optic nerve head 668392 1.1.1.35 3-hydroxyacyl-CoA dehydrogenase astrocyte activated, high level expression 673340 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase astrocyte - 763094 1.1.1.42 isocitrate dehydrogenase (NADP+) astrocyte - 656588 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase astrocyte major site for expression 763514 1.1.1.95 phosphoglycerate dehydrogenase astrocyte - 738901 1.11.1.27 glutathione-dependent peroxiredoxin astrocyte - 765401 1.11.1.9 glutathione peroxidase astrocyte - 685439, 686868 1.13.11.11 tryptophan 2,3-dioxygenase astrocyte - 743358 1.13.11.31 arachidonate 12-lipoxygenase astrocyte - 705902 1.13.11.52 indoleamine 2,3-dioxygenase astrocyte - 657493, 743358 1.13.11.6 3-hydroxyanthranilate 3,4-dioxygenase astrocyte - 439372, 439373 1.14.13.39 nitric-oxide synthase (NADPH) astrocyte - -, 693776, 699996, 764565 1.14.13.8 flavin-containing monooxygenase astrocyte prepared from forebrain of 1-day old Swiss Webster mice 440389 1.14.14.16 steroid 21-monooxygenase astrocyte cultured cell 658359 1.14.14.25 cholesterol 24-hydroxylase astrocyte - -, 705920, 712120 1.14.14.25 cholesterol 24-hydroxylase astrocyte in normal brain 659374 1.14.14.25 cholesterol 24-hydroxylase astrocyte primary 712816 1.14.15.15 cholestanetriol 26-monooxygenase astrocyte primary astrocytes express different sterol hydroxylases and are able to uptake exogenous 27-hydroxycholesterol 705935 1.16.3.1 ferroxidase astrocyte of cortex 689209 1.2.1.105 2-oxoglutarate dehydrogenase system astrocyte - 673870, 758628 1.2.1.12 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) astrocyte primary culture 743688 1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+) astrocyte - 763330 1.2.1.25 branched-chain alpha-keto acid dehydrogenase system astrocyte - 763513 1.2.1.25 branched-chain alpha-keto acid dehydrogenase system astrocyte primary cortical astrocyte cultures -, 763378 1.2.1.36 retinal dehydrogenase astrocyte - 725461 1.21.99.3 thyroxine 5-deiodinase astrocyte cell culture 644801 1.21.99.3 thyroxine 5-deiodinase astrocyte isozyme type III 644801 1.21.99.4 thyroxine 5'-deiodinase astrocyte - 715743 1.21.99.4 thyroxine 5'-deiodinase astrocyte cell culture 686407 1.3.1.24 biliverdin reductase astrocyte - 673797 1.3.8.1 short-chain acyl-CoA dehydrogenase astrocyte - 713043, 725641 1.4.1.27 glycine cleavage system astrocyte in rat brain, the P-protein is confined to astrocytes. The intensity of astrocyte staining varies with regions, with the strongest staining in the hippocampus, the cerebellar cortex, the Bergmann glia in the cerebellum and the Muller cells in the retina 758982 1.4.1.27 glycine cleavage system astrocyte molar ratios of P-, T-, and H-protein mRNA in cerebrocortical astrocyte culture are 5.7:1.0:2.4 758983 1.4.1.3 glutamate dehydrogenase [NAD(P)+] astrocyte - 762783, 763376 1.4.1.3 glutamate dehydrogenase [NAD(P)+] astrocyte high GDH2 expression level 712431 1.4.1.3 glutamate dehydrogenase [NAD(P)+] astrocyte predominantly 656871 1.4.3.13 protein-lysine 6-oxidase astrocyte - 689199 1.4.3.3 D-amino-acid oxidase astrocyte - 674360, 687746, 711720 1.4.3.3 D-amino-acid oxidase astrocyte in lower brain stem and cerebellum, as well as type-1 astrocytes from cerebral cortex and the cerebellum 712324 1.4.3.4 monoamine oxidase astrocyte MAO-B elevation in mouse brain astrocytes results in Parkinsons pathology 689716 1.5.1.1 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H] astrocyte - 743355 1.5.1.2 pyrroline-5-carboxylate reductase astrocyte - 743355 1.5.1.21 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) astrocyte - 743355 1.5.1.25 thiomorpholine-carboxylate dehydrogenase astrocyte - 743355 1.6.3.1 NAD(P)H oxidase (H2O2-forming) astrocyte - 672959 1.6.3.1 NAD(P)H oxidase (H2O2-forming) astrocyte involvement of reactive oxygen species from NADPH oxidase in cytokine induction of secretory phospholipase A2-IIA in astrocytes 700427 1.6.3.1 NAD(P)H oxidase (H2O2-forming) astrocyte isoforms NOX2 and NOX4 742567 1.6.3.1 NAD(P)H oxidase (H2O2-forming) astrocyte primary culture. Proliferation induced by fibrillar beta-amyloid peptide Abeta1-40 is mediated both by microglial release of TNF-alpha and by production of hydrogen peroxide by enzyme 675531 1.6.5.2 NAD(P)H dehydrogenase (quinone) astrocyte enzyme is highly upregulated in active and chronic multiple sclerosis lesions, particularly in hypertrophic astrocytes and myelin-laden macrophages 673798 1.8.1.7 glutathione-disulfide reductase astrocyte - -, 659860, 686856 1.8.5.1 glutathione dehydrogenase (ascorbate) astrocyte perivascular 394026 2.1.1.2 guanidinoacetate N-methyltransferase astrocyte - 688183 2.1.1.2 guanidinoacetate N-methyltransferase astrocyte moderate expression levels throughout development 757807 2.1.1.320 type II protein arginine methyltransferase astrocyte - 734170 2.1.1.63 methylated-DNA-[protein]-cysteine S-methyltransferase astrocyte - 672916 2.1.1.63 methylated-DNA-[protein]-cysteine S-methyltransferase astrocyte level of AGT is much reduced in mice lacking p53 673219 2.1.1.63 methylated-DNA-[protein]-cysteine S-methyltransferase astrocyte low activity 485498 2.1.1.63 methylated-DNA-[protein]-cysteine S-methyltransferase astrocyte MGMT gene expression is substantially lower in knockout p53 astrocytes than in wild-type p53 astrocytes 672916 2.1.1.67 thiopurine S-methyltransferase astrocyte primary cell 720847 2.1.1.8 histamine N-methyltransferase astrocyte - 704009 2.1.4.1 glycine amidinotransferase astrocyte - 686537 2.1.4.1 glycine amidinotransferase astrocyte adult brain 690097 2.2.1.1 transketolase astrocyte at the lesion border 694176 2.3.1.21 carnitine O-palmitoyltransferase astrocyte isoforms CPT1a and CPT2 are expressed exclusively by astrocytes 757462 2.3.1.43 phosphatidylcholine-sterol O-acyltransferase astrocyte - 736889 2.3.1.50 serine C-palmitoyltransferase astrocyte increased SPT enzyme activity in reactive astrocytes of the hippocampus at 2 weeks post-kainate injection 675555 2.3.1.50 serine C-palmitoyltransferase astrocyte primary rat cortical astrocytes -, 736885 2.3.1.6 choline O-acetyltransferase astrocyte - 737113 2.3.1.B41 protein-long-chain fatty-acyl-lysine deacylase (NAD+) astrocyte - 756691 2.3.2.13 protein-glutamine gamma-glutamyltransferase astrocyte insulin-like growth factor-I, epidermal growth factor, and insulin markedly increase TG-2 expression and activity. This effect is reduced when glial cultures are primed with both dexamethasone and estradiol. The regulation of TG-2 in astrocytes is signal- and hormone dependent 688551 2.3.2.2 gamma-glutamyltransferase astrocyte - 755785 2.3.2.5 glutaminyl-peptide cyclotransferase astrocyte - 735715 2.4.1.1 glycogen phosphorylase astrocyte expression of both muscle isoform and phosphorylase BB 672848 2.4.1.133 xylosylprotein 4-beta-galactosyltransferase astrocyte in the lesion site after spinal cord injury 704802 2.4.1.133 xylosylprotein 4-beta-galactosyltransferase astrocyte primary type 2 703134 2.4.1.17 glucuronosyltransferase astrocyte - 721077 2.4.1.174 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase astrocyte - 759849 2.4.1.214 glycoprotein 3-alpha-L-fucosyltransferase astrocyte - 661837 2.4.1.38 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase astrocyte - 719592 2.4.1.38 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase astrocyte primary 688471 2.4.1.90 N-acetyllactosamine synthase astrocyte - 757808 2.4.1.92 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase astrocyte - 688514 2.4.2.3 uridine phosphorylase astrocyte primary 676187 2.4.3.8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase astrocyte in primary neurons and astrocytes lacking GD3 synthase, amyloid beta-induced cell death and amyloid beta aggregation are inhibited 689168 2.5.1.16 spermidine synthase astrocyte - 675523 2.6.1.13 ornithine aminotransferase astrocyte - 758876 2.6.1.19 4-aminobutyrate-2-oxoglutarate transaminase astrocyte - 702961 2.6.1.42 branched-chain-amino-acid transaminase astrocyte - 640019, 640025 2.6.1.64 glutamine-phenylpyruvate transaminase astrocyte - 288890 2.6.1.7 kynurenine-oxoglutarate transaminase astrocyte - 759251 2.6.1.7 kynurenine-oxoglutarate transaminase astrocyte astrocytes in the substantia nigra express KAT-I under normal conditions. The amount of this enzyme increases after administration of 6-hydroxydopamine 671174 2.7.1.1 hexokinase astrocyte cerebrocortical astrocytes in primary culture, prepared from the neopallium 640248 2.7.1.1 hexokinase astrocyte hexokinase I: predominant in normal brain, hexokinase II: increased in brain tumors, ethylnitrosourea-induced 36B-10 astrocytic F-344 rat brain tumor cell line 640259 2.7.1.127 inositol-trisphosphate 3-kinase astrocyte cerebral cortex astrocytes, isoform B 640758 2.7.1.127 inositol-trisphosphate 3-kinase astrocyte highest expression of recombinant isoenzyme A in astrocytes of hippocampal cultures transfected with isoenzyme A 640760 2.7.1.137 phosphatidylinositol 3-kinase astrocyte - -, 707930, 708599 2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase astrocyte - 761163 2.7.1.20 adenosine kinase astrocyte astrocyte-based ADK provides a critical link between astrogliosis and neuronal dysfunction in epilepsy 687973 2.7.1.20 adenosine kinase astrocyte expressed most strongly in astrocytes 676193 2.7.1.59 N-acetylglucosamine kinase astrocyte low expression 739070 2.7.10.1 receptor protein-tyrosine kinase astrocyte - 490550 2.7.11.10 IkappaB kinase astrocyte - 694136 2.7.11.13 protein kinase C astrocyte - 693314, 725768 2.7.11.13 protein kinase C astrocyte primary, cortical 661460 2.7.11.2 [pyruvate dehydrogenase (acetyl-transferring)] kinase astrocyte - 761984 2.7.11.24 mitogen-activated protein kinase astrocyte - 697804, 702065 2.7.11.25 mitogen-activated protein kinase kinase kinase astrocyte - 742223 2.7.3.2 creatine kinase astrocyte - 737427, 761135 2.7.7.15 choline-phosphate cytidylyltransferase astrocyte - -, 721714 2.7.7.83 UDP-N-acetylgalactosamine diphosphorylase astrocyte - 722110 2.8.1.2 3-mercaptopyruvate sulfurtransferase astrocyte - 739470 2.8.2.17 chondroitin 6-sulfotransferase astrocyte - 738897 3.1.1.23 acylglycerol lipase astrocyte primary 666129 3.1.1.4 phospholipase A2 astrocyte - 653367 3.1.3.21 glycerol-1-phosphatase astrocyte - 681523 3.1.3.3 phosphoserine phosphatase astrocyte - 682867 3.1.3.5 5'-nucleotidase astrocyte - -, 715987, 750661 3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase astrocyte primary astrocyte, expression of wild-type enzyme 650911 3.1.3.74 pyridoxal phosphatase astrocyte - -, 715124 3.1.3.74 pyridoxal phosphatase astrocyte 4-5 days after ischemia PLP-P expressed in glial components 679694 3.1.3.9 glucose-6-phosphatase astrocyte - 750367 3.1.3.9 glucose-6-phosphatase astrocyte low enzyme activities 649729 3.1.3.9 glucose-6-phosphatase astrocyte primary 665603 3.1.4.11 phosphoinositide phospholipase C astrocyte - 681021, 682552, 715713 3.1.4.11 phosphoinositide phospholipase C astrocyte adult brain, PLC-delta1 is concentrated in astroglial cells, much lower levels in neurons 653442 3.1.4.11 phosphoinositide phospholipase C astrocyte PI-PLC delta3 681021 3.1.4.11 phosphoinositide phospholipase C astrocyte PLC-gamma1 mRNA is widely detected in various tissues. It is abundantly expressed in embryonal cortical structures, neurons, oligodendrocytes and astrocytes 691473 3.1.4.12 sphingomyelin phosphodiesterase astrocyte - 692073 3.1.4.12 sphingomyelin phosphodiesterase astrocyte cortical astrocyte, acid SMase 716445 3.1.4.35 3',5'-cyclic-GMP phosphodiesterase astrocyte - 652975 3.1.4.4 phospholipase D astrocyte - 708012 3.1.4.4 phospholipase D astrocyte primary 710112 3.1.6.12 N-acetylgalactosamine-4-sulfatase astrocyte - 729806 3.2.1.143 poly(ADP-ribose) glycohydrolase astrocyte cell culture 666771 3.2.1.143 poly(ADP-ribose) glycohydrolase astrocyte cortical cell culture 700897 3.2.1.143 poly(ADP-ribose) glycohydrolase astrocyte primary culture 664476 3.2.2.6 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase astrocyte - 731882 3.3.2.10 soluble epoxide hydrolase astrocyte - -, 699685, 710118, 731562, 753120 3.3.2.10 soluble epoxide hydrolase astrocyte cortical and hippocampal 707927 3.3.2.10 soluble epoxide hydrolase astrocyte scattered astrocyte 683721 3.3.2.9 microsomal epoxide hydrolase astrocyte - 699680, 699685, 710118, 753726 3.3.2.9 microsomal epoxide hydrolase astrocyte patchy distribution 661658 3.4.11.2 membrane alanyl aminopeptidase astrocyte - 665112 3.4.11.3 cystinyl aminopeptidase astrocyte - 753121 3.4.14.9 tripeptidyl-peptidase I astrocyte - 697808 3.4.17.10 carboxypeptidase E astrocyte cell culture 669606 3.4.17.21 Glutamate carboxypeptidase II astrocyte - 669923, 669962, 670363, 670397, 701258, 731257, 752980 3.4.17.21 Glutamate carboxypeptidase II astrocyte the level of glutamate carboxypeptidase II protein (GCPII) is regulated by valproic acid, a histone deacetylase (HDAC) inhibitor, through acetylation of lysine residue in the GCPII protein in human astrocytes, U-87MG 752648 3.4.17.23 angiotensin-converting enzyme 2 astrocyte transcriptional regulation of ACE2 mRNA in astrocytes is dependent on the relative concentrations of both angiotensin II and angiotensin(1–7) as well as on interaction with their respective receptors -, 667146 3.4.18.1 cathepsin X astrocyte - 683448 3.4.19.12 ubiquitinyl hydrolase 1 astrocyte - 710451 3.4.21.109 matriptase astrocyte - 717799 3.4.21.68 t-Plasminogen activator astrocyte - -, 718266, 718403 3.4.21.7 plasmin astrocyte plasmin evokes an increase in both phosphoinositide hydrolysis and Fura-2/AM fluorescence in cultured cortical astrocytes. Plasmin activiates extracellular signal-regulated kinase and induces a rise in intracellular Ca2+ concentration and phopho-ERK1/2 levels 698776 3.4.21.75 Furin astrocyte primary cortical -, 732368 3.4.21.B10 neurosin astrocyte primary cell culture 731396 3.4.21.B7 mannan-binding lectin-associated serine protease 1 astrocyte - 666927 3.4.22.1 cathepsin B astrocyte - 707002 3.4.22.27 cathepsin S astrocyte - 696995 3.4.22.36 caspase-1 astrocyte - 681931 3.4.22.56 caspase-3 astrocyte primary 700938 3.4.22.60 caspase-7 astrocyte primary 700938 3.4.22.61 caspase-8 astrocyte - 697771, 710108 3.4.22.61 caspase-8 astrocyte no change in activity after irradiation 664508 3.4.22.64 caspase-11 astrocyte - 664925, 708506, 709623 3.4.22.B25 calpain 5 astrocyte - -, 732139 3.4.22.B72 SENP3 peptidase astrocyte - -, 731627, 731628 3.4.23.45 memapsin 1 astrocyte - 754574 3.4.23.46 memapsin 2 astrocyte astrocytic BACE1 expression may be important to the development of pathology in Alzheimer's disease 669930 3.4.23.5 cathepsin D astrocyte - 711354, 713109, 753898 3.4.24.16 neurolysin astrocyte - 37080, 37082 3.4.24.16 neurolysin astrocyte contain only soluble enzyme 37076 3.4.24.35 gelatinase B astrocyte - 710106, 734590 3.4.24.35 gelatinase B astrocyte enzyme expression is slightly induced by HIV and strongly induced by TNF alpha, while matrix metalloproteinase MMP-2 and tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 are only slightly affected. Astrocytes are a major source of enzyme in the inflamed brain 670149 3.4.24.35 gelatinase B astrocyte secretion, induced by interleukin-1beta 683874 3.4.24.56 insulysin astrocyte primary 683801 3.4.24.71 endothelin-converting enzyme 1 astrocyte - 684002 3.4.24.71 endothelin-converting enzyme 1 astrocyte lower expression of ECE-1 710094 3.4.24.81 ADAM10 endopeptidase astrocyte strain U373 MG 669957 3.4.24.82 ADAMTS-4 endopeptidase astrocyte - 668117 3.4.24.82 ADAMTS-4 endopeptidase astrocyte cell culture, expression of aggrecanase-1 mRNA is induced if cells are treated with beta-amyloid 638959 3.4.24.86 ADAM 17 endopeptidase astrocyte - 639002 3.4.24.87 ADAMTS13 endopeptidase astrocyte in cerebral corpora amylacea, that occur in aging brains and in patients with neurodegenerative conditions 713116 3.4.24.B10 ADAM12 endopeptidase astrocyte - 711642 3.4.24.B11 ADAMTS1 endopeptidase astrocyte - 668117 3.4.24.B18 m-AAA protease astrocyte - 753753 3.4.24.B4 matrix metalloproteinase-13 astrocyte MMP-13 is mainly produced by neurons, but also by astrocytes 693332 3.4.24.B4 matrix metalloproteinase-13 astrocyte primary 712559 3.4.24.B7 matrix metalloproteinase-26 astrocyte astrocytic gliom tissue 754946 3.4.25.1 proteasome endopeptidase complex astrocyte - 711354 3.4.25.1 proteasome endopeptidase complex astrocyte differentiated from C6 glioma cells -, 720289 3.4.25.1 proteasome endopeptidase complex astrocyte from subjects with Alexander disease 712414 3.5.1.2 glutaminase astrocyte isozymes LGA and KGA 670391 3.5.1.2 glutaminase astrocyte phosphate-activated isozyme 670129 3.5.1.3 omega-amidase astrocyte omega-amidase activity is about the same in cultured chick astrocytes and neurons 288890 3.5.1.3 omega-amidase astrocyte omega-amidase activity is higher in astrocytes than in neurons 288890 3.5.1.3 omega-amidase astrocyte omega-amidase activity is significantly higher in astrocytes than in neurons 288890 3.5.1.3 omega-amidase astrocyte primary cultures of astrocytes 288890 3.5.3.15 protein-arginine deiminase astrocyte - 663848, 666136, 697491 3.5.3.15 protein-arginine deiminase astrocyte cortical 686367 3.5.3.15 protein-arginine deiminase astrocyte PAD2 immunoreactivity is increased in Scrapie-infected brains, with staining detected primarily in reactive astrocytes 695453 3.5.3.15 protein-arginine deiminase astrocyte pressure-treated astrocytes exhibit elevated PAD2 and citrullination without apparent change in PAD2 mRNA 665252 3.5.4.16 GTP cyclohydrolase I astrocyte - 701141 3.5.4.6 AMP deaminase astrocyte similar level of expression of AMPD2, but greater expression of AMPD3 than in neurons 669960 3.6.1.9 nucleotide diphosphatase astrocyte - 756172 4.1.1.17 ornithine decarboxylase astrocyte primary cells 680257 4.2.1.22 cystathionine beta-synthase astrocyte cystathionine beta-synthase is associated with the generation and/or differentiation of the radial glia/astrocyte lineage cells in the developing central nervous system 664879 4.3.2.1 argininosuccinate lyase astrocyte - 650743 4.4.1.1 cystathionine gamma-lyase astrocyte - 710063 4.6.1.1 adenylate cyclase astrocyte - 681092 4.6.1.2 guanylate cyclase astrocyte - -, 693776 5.1.1.18 serine racemase astrocyte - 682127, 682561, 706532, 714348, 716344, 747183, 747888, 747903 5.1.1.18 serine racemase astrocyte from forebrain, very low expression level 727279 5.1.1.18 serine racemase astrocyte of optic nerve 690635 5.1.1.18 serine racemase astrocyte protoplasmic 728034 5.3.99.2 Prostaglandin-D synthase astrocyte lipocalin-type prostaglandin D synthase (beta-trace) is upregulated in the alphaB-crystallin-positive astrocytes in the chronic multiple sclerosis 662954 5.3.99.3 prostaglandin-E synthase astrocyte - 690320 6.2.1.3 long-chain-fatty-acid-CoA ligase astrocyte - 675554 6.3.1.2 glutamine synthetase astrocyte - 691547, 692129, 692519, 694406, 695162, 745832 6.3.1.2 glutamine synthetase astrocyte astrocyte-specific glutamine synthetase 692128 6.3.1.2 glutamine synthetase astrocyte cultured cortical astrocytes maintained with endothelins show an almost complete loss of glutamine synthetase 693781 6.3.1.2 glutamine synthetase astrocyte primary 693726 6.3.1.2 glutamine synthetase astrocyte primary cell culture 716350 6.3.2.2 glutamate-cysteine ligase astrocyte - 673803 6.3.2.2 glutamate-cysteine ligase astrocyte primary astrocyte 715084 6.3.2.2 glutamate-cysteine ligase astrocyte primary cell culture 649315 6.3.2.3 glutathione synthase astrocyte primary cortical astrocytes 693731 6.3.2.41 N-acetylaspartylglutamate synthase astrocyte - 727869, 728179 6.4.1.1 pyruvate carboxylase astrocyte - 690828 7.1.1.9 cytochrome-c oxidase astrocyte cortical astrocyte. Differential, cell-type specific expression of enzyme subunit IV isoform 2 in cortical astrocytes and cerebellar neurons. Presence of subunit IV isoform 2 suppresses the sensitivity of enzyme to its allosteric regulator ATP and overrules the regulation by the cellular energy level. Pivotal role of enzyme as an oxygen sensor in brain 675529 7.2.2.13 Na+/K+-exchanging ATPase astrocyte - 713111 7.2.2.9 P-type Cu2+ transporter astrocyte - 670415