EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
3.1.1.23 | acylglycerol lipase |
adipocyte |
- |
94261, 94269 |
3.1.1.3 | triacylglycerol lipase |
adipocyte |
- |
693072, 707547, 708339, 708593, 709226, 709776, 728937, 729337 |
3.1.1.3 | triacylglycerol lipase |
adipocyte |
hormone-sensitive lipase is negatively regulated by perilipin, lipolysis of storage triacylglycerides |
664561 |
3.1.1.3 | triacylglycerol lipase |
adipocyte |
hormone-sensitive lipase, lipolysis of storage triacylglycerides |
664561 |
3.1.1.34 | lipoprotein lipase |
adipocyte |
- |
-, 652702, 690827, 693527, 709009, 729291, 751275, 80891 |
3.1.1.4 | phospholipase A2 |
adipocyte |
- |
751474 |
3.1.1.47 | 1-alkyl-2-acetylglycerophosphocholine esterase |
adipocyte |
- |
653094 |
3.1.1.79 | hormone-sensitive lipase |
adipocyte |
- |
-, 665562, 665964, 677942, 714034, 714319, 714794 |
3.1.1.79 | hormone-sensitive lipase |
adipocyte |
adipocytes retrovirally engineered from murine embryonic fibroblasts |
680650 |
3.1.1.79 | hormone-sensitive lipase |
adipocyte |
dydrogesterone and norethisterone regulate expression of hormone-sensitive lipase in human subcutaneous abdominal adipocytes |
679453 |
3.1.1.79 | hormone-sensitive lipase |
adipocyte |
women with polycystic ovary syndrome or obesity have significantly decreased expression of hormone-sensitive lipase. Knock down of hormone-sensitive lipase by RNAi reduces basal and catecholamine-induced lipolysis. Treatment of mesenchymal stem cells with a selective inhibitor of hormone-sensitive lipase during and/or after differentiation in adipocytes reduces basal lipolysis by 50% |
677465 |
3.1.3.108 | nocturnin |
adipocyte |
highly expressed in differentiating adipocytes. When adipocyte differentiation is complete there is two fold increase in nocturnin protein compared to undifferentiated controls |
755795 |
3.1.3.16 | protein-serine/threonine phosphatase |
adipocyte |
- |
691879 |
3.1.3.36 | phosphoinositide 5-phosphatase |
adipocyte |
- |
677869 |
3.1.3.36 | phosphoinositide 5-phosphatase |
adipocyte |
72-5ptase is expressed in differentiated 3T3-L1 adipocytes |
678074 |
3.1.3.4 | phosphatidate phosphatase |
adipocyte |
- |
666926, 680814, 709417, 709419, 709945, 710639, 714316 |
3.1.3.46 | fructose-2,6-bisphosphate 2-phosphatase |
adipocyte |
inducible expression of isozyme PFKFB3 |
664718 |
3.1.3.46 | fructose-2,6-bisphosphate 2-phosphatase |
adipocyte |
inducible expression of isozyme PFKFB3, visceral fat cell |
664718 |
3.1.3.48 | protein-tyrosine-phosphatase |
adipocyte |
- |
652081, 730970 |
3.1.3.67 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase |
adipocyte |
- |
677869, 694494 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
adipocyte |
- |
716435 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
adipocyte |
primary |
668230 |
3.1.4.39 | alkylglycerophosphoethanolamine phosphodiesterase |
adipocyte |
- |
729338 |
3.1.4.39 | alkylglycerophosphoethanolamine phosphodiesterase |
adipocyte |
Immunocyto-fluorescence microscopy reveals that ATX is detected in 3T3F442A adipocytes and is almost undetectable in 3T3F442A preadipocytes. 3T3F442A mouse preadipose cell line |
678439 |
3.1.8.1 | aryldialkylphosphatase |
adipocyte |
PON1 |
692441 |
3.3.2.10 | soluble epoxide hydrolase |
adipocyte |
- |
732301 |
3.3.2.10 | soluble epoxide hydrolase |
adipocyte |
sEH is synthesized in adipocytes and expression levels increase upon differentiation of 3T3-L1 preadipocytes. Although normalized sEH mRNA and protein levels do not differ in the fat pads from mice receiving a regular or a high-fat diet, total adipose sEH activity is higher in the obese mice. Peroxisome proliferator-activated receptor gamma agonists increase the expression of sEH in mature 3T3-L1 adipocytes in vitro and in adipose tissue in vivo |
716401 |
3.3.2.6 | leukotriene-A4 hydrolase |
adipocyte |
- |
647020 |
3.4.11.1 | leucyl aminopeptidase |
adipocyte |
- |
651776, 664275, 664276, 752649 |
3.4.11.3 | cystinyl aminopeptidase |
adipocyte |
- |
-, 668760, 683048, 709666, 753943, 754109, 754445, 755404 |
3.4.15.1 | peptidyl-dipeptidase A |
adipocyte |
- |
700299 |
3.4.17.12 | carboxypeptidase M |
adipocyte |
- |
697395 |
3.4.21.46 | complement factor D |
adipocyte |
- |
755129 |
3.4.22.27 | cathepsin S |
adipocyte |
- |
668538, 699142 |
3.4.22.38 | cathepsin K |
adipocyte |
CTSK is active mainly in the early stages of adipogenesis |
697619 |
3.4.22.52 | calpain-1 |
adipocyte |
- |
707364 |
3.4.22.B30 | calpain 10 |
adipocyte |
- |
731226 |
3.4.22.B70 | SENP1 peptidase |
adipocyte |
- |
732144 |
3.4.22.B71 | SENP2 peptidase |
adipocyte |
- |
754442 |
3.4.23.15 | renin |
adipocyte |
- |
753983 |
3.4.24.11 | neprilysin |
adipocyte |
adipocyte membrane |
685866 |
3.4.24.80 | membrane-type matrix metalloproteinase-1 |
adipocyte |
- |
753384 |
3.4.24.80 | membrane-type matrix metalloproteinase-1 |
adipocyte |
of mammary gland |
753384 |
3.4.24.81 | ADAM10 endopeptidase |
adipocyte |
- |
708278 |
3.4.24.86 | ADAM 17 endopeptidase |
adipocyte |
adipose tissue |
639013 |
3.4.24.B10 | ADAM12 endopeptidase |
adipocyte |
- |
680191 |
3.4.24.B5 | matrix metalloproteinase-15 |
adipocyte |
- |
753384 |
3.4.24.B5 | matrix metalloproteinase-15 |
adipocyte |
of mammary gland |
753384 |
3.6.5.1 | heterotrimeric G-protein GTPase |
adipocyte |
Go-alpha subunit |
644099 |
3.6.5.2 | small monomeric GTPase |
adipocyte |
- |
699992, 701352 |
4.1.1.29 | sulfinoalanine decarboxylase |
adipocyte |
- |
693792 |
4.1.1.32 | phosphoenolpyruvate carboxykinase (GTP) |
adipocyte |
- |
694251 |
4.1.1.32 | phosphoenolpyruvate carboxykinase (GTP) |
adipocyte |
rodent adipocyte |
693786 |
4.4.1.1 | cystathionine gamma-lyase |
adipocyte |
- |
690781 |
4.6.1.1 | adenylate cyclase |
adipocyte |
- |
34802 |
4.6.1.14 | glycosylphosphatidylinositol diacylglycerol-lyase |
adipocyte |
- |
648771, 648772, 661039, 691540 |
5.2.1.8 | peptidylprolyl isomerase |
adipocyte |
- |
715609 |
5.3.3.12 | L-dopachrome isomerase |
adipocyte |
- |
728570 |
5.3.3.8 | DELTA3-DELTA2-enoyl-CoA isomerase |
adipocyte |
- |
706005 |
5.3.99.2 | Prostaglandin-D synthase |
adipocyte |
- |
694939 |
6.2.1.16 | acetoacetate-CoA ligase |
adipocyte |
- |
-, 691065, 702149, 744226 |
6.2.1.16 | acetoacetate-CoA ligase |
adipocyte |
AACS mRNA is preferentially detected in mature adipocytes but not in preadipocytes. AACS mRNA expression in primary preadipocytes increases during the adipocyte differentiation |
660915 |
6.2.1.3 | long-chain-fatty-acid-CoA ligase |
adipocyte |
- |
662593, 662994, 714678 |
6.4.1.1 | pyruvate carboxylase |
adipocyte |
tight regulation of enzyme expression with differentiation |
690828 |
6.4.1.2 | acetyl-CoA carboxylase |
adipocyte |
- |
666733 |