1.1.1.146 11beta-hydroxysteroid dehydrogenase adipocyte - 668379, 669504, 697625, 700121, 700179, 700180, 712594, 740806 1.1.1.146 11beta-hydroxysteroid dehydrogenase adipocyte epididymal fat, presence of a functional glucose-6-phosphate-transporter hexose-6-phosphate dehydrogenase 11beta-hydroxysteroid dehydrogenase type 1 system 692078 1.1.1.146 11beta-hydroxysteroid dehydrogenase adipocyte methionine restriction induces isoform 11beta-HSD1 activity in all types of adipose tissue examined, correlating with increased tissue corticosterone. Inverse relationship between 11beta-HSD1 activity and adipocyte size is observed. Methionine restriction additionally increases adipose triglyceride lipase and acetyl-coenzyme A carboxylase protein levels 688225 1.1.1.205 IMP dehydrogenase adipocyte - 702061 1.1.1.42 isocitrate dehydrogenase (NADP+) adipocyte - 656247, 761047 1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) adipocyte - 667411, 685541 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase adipocyte real-time RT-PCR expression 17beta-HSD type 2 analysis 741000 1.1.1.62 17beta-estradiol 17-dehydrogenase adipocyte - 699843 1.1.1.8 glycerol-3-phosphate dehydrogenase (NAD+) adipocyte - 699948 1.1.1.95 phosphoglycerate dehydrogenase adipocyte - 287528 1.1.1.B40 11beta-hydroxysteroid dehydrogenase (NAD+) adipocyte - 668379 1.11.1.9 glutathione peroxidase adipocyte pGPx is expressed during bovine adipocyte differentiation, transcriptional control of pGPx in cattle might be carried out by C/EBPdelta 672988 1.13.11.20 cysteine dioxygenase adipocyte - 695529 1.13.11.31 arachidonate 12-lipoxygenase adipocyte - 743718 1.13.11.33 arachidonate 15-lipoxygenase adipocyte - 742239, 743718 1.13.11.63 beta-carotene 15,15'-dioxygenase adipocyte - 728342, 728552 1.14.11.4 procollagen-lysine 5-dioxygenase adipocyte - 745769 1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase adipocyte - 753372 1.14.15.18 calcidiol 1-monooxygenase adipocyte - 699840 1.14.19.1 stearoyl-CoA 9-desaturase adipocyte - 687766, 746212 1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase adipocyte - 754828 1.2.1.104 pyruvate dehydrogenase system adipocyte - 760172 1.2.1.104 pyruvate dehydrogenase system adipocyte brown adipocyte 762889 1.2.4.1 pyruvate dehydrogenase (acetyl-transferring) adipocyte brown adipocyte 762889 1.21.99.3 thyroxine 5-deiodinase adipocyte cell culture 644799 1.21.99.3 thyroxine 5-deiodinase adipocyte isozyme type III 644799 1.21.99.4 thyroxine 5'-deiodinase adipocyte - 644806 1.21.99.4 thyroxine 5'-deiodinase adipocyte isozyme type II 644806 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase adipocyte - 687562 1.3.3.6 acyl-CoA oxidase adipocyte - 671758 1.3.8.7 medium-chain acyl-CoA dehydrogenase adipocyte - 656794 1.3.99.23 all-trans-retinol 13,14-reductase adipocyte - 700994, 763507 1.4.3.21 primary-amine oxidase adipocyte - 689376, 701561, 701612, 726290 1.4.3.21 primary-amine oxidase adipocyte major SSAO form expressed in mouse adipocytes is encoded by the AOC3 gene 688487 1.4.3.21 primary-amine oxidase adipocyte most of the SSAO found in adipose tissue originates from mature adipocytes 688255 1.4.3.21 primary-amine oxidase adipocyte SSAO inhibition is not sufficient to impair fat deposition. However, combined monoamine oxidase (EC 1.4.3.4) inhibition and SSAO inhibition limits adiposity in non-obese as well as in obese rats 689377 1.4.3.21 primary-amine oxidase adipocyte the major SSAO form expressed in mouse adipocytes is encoded by the AOC3 gene 688487 1.4.3.4 monoamine oxidase adipocyte - 689376 1.4.3.4 monoamine oxidase adipocyte in human subcutaneous adipose tissue, the adipocyte-enriched fraction exhibits seven-fold higher amine oxidase activity and contains 3- to 7-fold higher levels of mRNAs encoded by MAO-A and MAO-B genes than the stroma-vascular fraction. MAO-A gene accounts for the majority of the respective MAO and SSAO activities in human adipose tissue. Most of the SSAO and MAO found in adipose tissue originated from mature adipocytes 685418 1.4.3.4 monoamine oxidase adipocyte most of the monoamine oxidase found in adipose tissue originates from mature adipocytes 688255 1.4.3.4 monoamine oxidase adipocyte SSAO inhibition is not sufficient to impair fat deposition. Combined MAO and SSAO inhibition limits adiposity in non-obese as well as in obese rats 689377 1.6.3.1 NAD(P)H oxidase (H2O2-forming) adipocyte isoform Nox4 is expressed at high levels in white and brown preadipocytes. Differentiation into adipocytes results in a decrease in their NOX4 mRNA content. In intact adipose tissue, the majority of NOX4 expressing cells are localized within the preadipocyte containing stromal/vascular fracftion. Alterations in NOX4 expression reflects changes in the ratio of adipocyte/interstitial fractions 685345 2.1.1.1 nicotinamide N-methyltransferase adipocyte - 701990 2.1.1.1 nicotinamide N-methyltransferase adipocyte NNMT expression profile, overview 701990 2.1.1.204 tRNA (cytosine38-C5)-methyltransferase adipocyte - -, 736018 2.1.1.319 type I protein arginine methyltransferase adipocyte Prmt1 is highly expressed in major metabolic organs and cell types, including thermogenic fat tissue and adipocytes 756600 2.1.1.348 mRNA m6A methyltransferase adipocyte - 757661 2.3.1.108 alpha-tubulin N-acetyltransferase adipocyte acetylation of alpha-tubulin is up-regulated during adipogenesis, and adipocyte development is dependent on alpha-tubulin acetylation 735631 2.3.1.15 glycerol-3-phosphate 1-O-acyltransferase adipocyte - 701623, 702011, 756106 2.3.1.15 glycerol-3-phosphate 1-O-acyltransferase adipocyte GPAT3 mRNA is dramatically upregulated during adipocyte differentiation 676839 2.3.1.15 glycerol-3-phosphate 1-O-acyltransferase adipocyte mitochondrial acyltransferase 486376 2.3.1.15 glycerol-3-phosphate 1-O-acyltransferase adipocyte the expression of GPAT2 is downregulated when 3T3-L1 cells differentiate into adipocytes, while GPAT1, 3, and 4 are upregulated (10fold, over 60, and 5fold, respectively) 757868 2.3.1.15 glycerol-3-phosphate 1-O-acyltransferase adipocyte the expression of GPAT2 is downregulated when 3T3-L1 cells differentiate into adipocytes, while GPAT1, 3, and 4 are upregulated 10fold, over 60fold, and 5fold, respectively 757868 2.3.1.20 diacylglycerol O-acyltransferase adipocyte - -, 486338, 486485, 486487, 486489, 486495, 486505, 486506, 486512, 486513 2.3.1.20 diacylglycerol O-acyltransferase adipocyte isolated from parametrial adipose 486484 2.3.1.21 carnitine O-palmitoyltransferase adipocyte - 486560, 486577 2.3.1.22 2-acylglycerol O-acyltransferase adipocyte - 757377 2.3.1.23 1-acylglycerophosphocholine O-acyltransferase adipocyte by retrieving LPCAT3 expression pattern from Genevestigator 688774 2.3.1.42 glycerone-phosphate O-acyltransferase adipocyte - 486338, 486955, 486974 2.3.1.51 1-acylglycerol-3-phosphate O-acyltransferase adipocyte - 671597, 756108, 756599 2.3.1.51 1-acylglycerol-3-phosphate O-acyltransferase adipocyte isozyme AGPAT2 674530 2.3.1.57 diamine N-acetyltransferase adipocyte - 757571 2.3.3.8 ATP citrate synthase adipocyte - 736797 2.4.1.11 glycogen(starch) synthase adipocyte 3T3-L1 488441, 488447 2.4.2.12 nicotinamide phosphoribosyltransferase adipocyte - 735872 2.4.3.1 beta-galactoside alpha-(2,6)-sialyltransferase adipocyte - 759485 2.5.1.60 protein geranylgeranyltransferase type II adipocyte - 638598 2.6.1.1 aspartate transaminase adipocyte - 674846 2.6.1.1 aspartate transaminase adipocyte differentiated from 3T3-L1 fibroblasts 639866 2.7.1.1 hexokinase adipocyte very low expression 703959 2.7.1.113 deoxyguanosine kinase adipocyte - 661040 2.7.1.137 phosphatidylinositol 3-kinase adipocyte - 640905, 640908, 640911, 640924, 709772 2.7.1.137 phosphatidylinositol 3-kinase adipocyte 3T3-L1 640849, 640863 2.7.1.137 phosphatidylinositol 3-kinase adipocyte during differentiation of 3T3-L1 cells into adipocytes, isoform p110b is up-regulated approximately 10-fold, expression of p110a is unaltered 640863 2.7.1.137 phosphatidylinositol 3-kinase adipocyte insulin-sensitive mouse 3T3-L1 adipocytes 640921 2.7.1.137 phosphatidylinositol 3-kinase adipocyte primary, obtained from subcutaneous tissue biopsies performed on two lean non-diabetic male subjects 709772 2.7.1.150 1-phosphatidylinositol-3-phosphate 5-kinase adipocyte - 660790 2.7.1.30 glycerol kinase adipocyte There is no difference in glycerol mRNA level between control 3T3-L1 adipocytes and 3T3-L1 Aqp7-RNAi transfected adipocytes, whereas a 4fold enzymatic activation of glycerol kinase is observable in Aqp7 knockout adipocytes (activity assay: 50 mM TrisHCl, pH 7.2, 5 mM ATP, 10 mM MgCl2, 100 mM KCl, 2.5 mM DTT, 4 mM glycerol, 500 microM 3H-glycerol, for 90 min at 37°C). 682503 2.7.1.40 pyruvate kinase adipocyte expression of M2-type pyruvate kinase isoenzyme 721787 2.7.1.67 1-phosphatidylinositol 4-kinase adipocyte - 641796, 676001 2.7.1.74 deoxycytidine kinase adipocyte - 661040 2.7.10.1 receptor protein-tyrosine kinase adipocyte - 671353 2.7.11.1 non-specific serine/threonine protein kinase adipocyte - -, 723027, 738003, 761503 2.7.11.1 non-specific serine/threonine protein kinase adipocyte white, brown and beige adipocyte 742242 2.7.11.11 cAMP-dependent protein kinase adipocyte - 671678, 693043, 694155 2.7.11.12 cGMP-dependent protein kinase adipocyte - 737600 2.7.11.13 protein kinase C adipocyte - 676029 2.7.11.15 beta-adrenergic-receptor kinase adipocyte - 661684, 724817 2.7.11.27 [acetyl-CoA carboxylase] kinase adipocyte - 761916 2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase adipocyte - 692365, 760351, 760910 2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase adipocyte primary 665636 2.7.11.4 [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase adipocyte - 640583 2.7.4.21 inositol-hexakisphosphate 5-kinase adipocyte - 738392 2.7.7.14 ethanolamine-phosphate cytidylyltransferase adipocyte - 671816 2.7.7.14 ethanolamine-phosphate cytidylyltransferase adipocyte high Pcyt2 mRNA content. Negligible amount of Pcyt2beta mRNA, high amount of Pcyt2alpha mRNA 671816 2.7.8.1 ethanolaminephosphotransferase adipocyte - 644323 2.7.8.2 diacylglycerol cholinephosphotransferase adipocyte - 644323 2.8.1.1 thiosulfate sulfurtransferase adipocyte - 739155 2.8.2.4 estrone sulfotransferase adipocyte - 725979 2.8.2.4 estrone sulfotransferase adipocyte EST is predominantly expressed in stromal vascular cells (pre-adipocytes). Consistent with the pre-adipocyte pattern of expression, the expression of EST is dramatically reduced in differentiated 3T3-L1 cells or mature primary adipocytes -, 760317 3.1.1.23 acylglycerol lipase adipocyte - 94261, 94269 3.1.1.3 triacylglycerol lipase adipocyte - 693072, 707547, 708339, 708593, 709226, 709776, 728937, 729337 3.1.1.3 triacylglycerol lipase adipocyte hormone-sensitive lipase is negatively regulated by perilipin, lipolysis of storage triacylglycerides 664561 3.1.1.3 triacylglycerol lipase adipocyte hormone-sensitive lipase, lipolysis of storage triacylglycerides 664561 3.1.1.34 lipoprotein lipase adipocyte - -, 652702, 690827, 693527, 709009, 729291, 751275, 80891 3.1.1.4 phospholipase A2 adipocyte - 751474 3.1.1.47 1-alkyl-2-acetylglycerophosphocholine esterase adipocyte - 653094 3.1.1.79 hormone-sensitive lipase adipocyte - -, 665562, 665964, 677942, 714034, 714319, 714794 3.1.1.79 hormone-sensitive lipase adipocyte adipocytes retrovirally engineered from murine embryonic fibroblasts 680650 3.1.1.79 hormone-sensitive lipase adipocyte dydrogesterone and norethisterone regulate expression of hormone-sensitive lipase in human subcutaneous abdominal adipocytes 679453 3.1.1.79 hormone-sensitive lipase adipocyte women with polycystic ovary syndrome or obesity have significantly decreased expression of hormone-sensitive lipase. Knock down of hormone-sensitive lipase by RNAi reduces basal and catecholamine-induced lipolysis. Treatment of mesenchymal stem cells with a selective inhibitor of hormone-sensitive lipase during and/or after differentiation in adipocytes reduces basal lipolysis by 50% 677465 3.1.3.108 nocturnin adipocyte highly expressed in differentiating adipocytes. When adipocyte differentiation is complete there is two fold increase in nocturnin protein compared to undifferentiated controls 755795 3.1.3.16 protein-serine/threonine phosphatase adipocyte - 691879 3.1.3.36 phosphoinositide 5-phosphatase adipocyte - 677869 3.1.3.36 phosphoinositide 5-phosphatase adipocyte 72-5ptase is expressed in differentiated 3T3-L1 adipocytes 678074 3.1.3.4 phosphatidate phosphatase adipocyte - 666926, 680814, 709417, 709419, 709945, 710639, 714316 3.1.3.46 fructose-2,6-bisphosphate 2-phosphatase adipocyte inducible expression of isozyme PFKFB3 664718 3.1.3.46 fructose-2,6-bisphosphate 2-phosphatase adipocyte inducible expression of isozyme PFKFB3, visceral fat cell 664718 3.1.3.48 protein-tyrosine-phosphatase adipocyte - 652081, 730970 3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase adipocyte - 677869, 694494 3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase adipocyte - 716435 3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase adipocyte primary 668230 3.1.4.39 alkylglycerophosphoethanolamine phosphodiesterase adipocyte - 729338 3.1.4.39 alkylglycerophosphoethanolamine phosphodiesterase adipocyte Immunocyto-fluorescence microscopy reveals that ATX is detected in 3T3F442A adipocytes and is almost undetectable in 3T3F442A preadipocytes. 3T3F442A mouse preadipose cell line 678439 3.1.8.1 aryldialkylphosphatase adipocyte PON1 692441 3.3.2.10 soluble epoxide hydrolase adipocyte - 732301 3.3.2.10 soluble epoxide hydrolase adipocyte sEH is synthesized in adipocytes and expression levels increase upon differentiation of 3T3-L1 preadipocytes. Although normalized sEH mRNA and protein levels do not differ in the fat pads from mice receiving a regular or a high-fat diet, total adipose sEH activity is higher in the obese mice. Peroxisome proliferator-activated receptor gamma agonists increase the expression of sEH in mature 3T3-L1 adipocytes in vitro and in adipose tissue in vivo 716401 3.3.2.6 leukotriene-A4 hydrolase adipocyte - 647020 3.4.11.1 leucyl aminopeptidase adipocyte - 651776, 664275, 664276, 752649 3.4.11.3 cystinyl aminopeptidase adipocyte - -, 668760, 683048, 709666, 753943, 754109, 754445, 755404 3.4.15.1 peptidyl-dipeptidase A adipocyte - 700299 3.4.17.12 carboxypeptidase M adipocyte - 697395 3.4.21.46 complement factor D adipocyte - 755129 3.4.22.27 cathepsin S adipocyte - 668538, 699142 3.4.22.38 cathepsin K adipocyte CTSK is active mainly in the early stages of adipogenesis 697619 3.4.22.52 calpain-1 adipocyte - 707364 3.4.22.B30 calpain 10 adipocyte - 731226 3.4.22.B70 SENP1 peptidase adipocyte - 732144 3.4.22.B71 SENP2 peptidase adipocyte - 754442 3.4.23.15 renin adipocyte - 753983 3.4.24.11 neprilysin adipocyte adipocyte membrane 685866 3.4.24.80 membrane-type matrix metalloproteinase-1 adipocyte - 753384 3.4.24.80 membrane-type matrix metalloproteinase-1 adipocyte of mammary gland 753384 3.4.24.81 ADAM10 endopeptidase adipocyte - 708278 3.4.24.86 ADAM 17 endopeptidase adipocyte adipose tissue 639013 3.4.24.B10 ADAM12 endopeptidase adipocyte - 680191 3.4.24.B5 matrix metalloproteinase-15 adipocyte - 753384 3.4.24.B5 matrix metalloproteinase-15 adipocyte of mammary gland 753384 3.6.5.1 heterotrimeric G-protein GTPase adipocyte Go-alpha subunit 644099 3.6.5.2 small monomeric GTPase adipocyte - 699992, 701352 4.1.1.29 sulfinoalanine decarboxylase adipocyte - 693792 4.1.1.32 phosphoenolpyruvate carboxykinase (GTP) adipocyte - 694251 4.1.1.32 phosphoenolpyruvate carboxykinase (GTP) adipocyte rodent adipocyte 693786 4.4.1.1 cystathionine gamma-lyase adipocyte - 690781 4.6.1.1 adenylate cyclase adipocyte - 34802 4.6.1.14 glycosylphosphatidylinositol diacylglycerol-lyase adipocyte - 648771, 648772, 661039, 691540 5.2.1.8 peptidylprolyl isomerase adipocyte - 715609 5.3.3.12 L-dopachrome isomerase adipocyte - 728570 5.3.3.8 DELTA3-DELTA2-enoyl-CoA isomerase adipocyte - 706005 5.3.99.2 Prostaglandin-D synthase adipocyte - 694939 6.2.1.16 acetoacetate-CoA ligase adipocyte - -, 691065, 702149, 744226 6.2.1.16 acetoacetate-CoA ligase adipocyte AACS mRNA is preferentially detected in mature adipocytes but not in preadipocytes. AACS mRNA expression in primary preadipocytes increases during the adipocyte differentiation 660915 6.2.1.3 long-chain-fatty-acid-CoA ligase adipocyte - 662593, 662994, 714678 6.4.1.1 pyruvate carboxylase adipocyte tight regulation of enzyme expression with differentiation 690828 6.4.1.2 acetyl-CoA carboxylase adipocyte - 666733