EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
3.1.3.16 | protein-serine/threonine phosphatase |
HL-60 cell |
- |
692550 |
3.1.3.16 | protein-serine/threonine phosphatase |
HL-60 cell |
a promyelocytic leukemia cell line |
698767 |
3.1.3.25 | inositol-phosphate phosphatase |
HL-60 cell |
- |
114225 |
3.1.3.86 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase |
HL-60 cell |
- |
714601 |
3.1.4.1 | phosphodiesterase I |
HL-60 cell |
- |
208356 |
3.1.4.11 | phosphoinositide phospholipase C |
HL-60 cell |
- |
678438, 679976, 682863 |
3.1.4.11 | phosphoinositide phospholipase C |
HL-60 cell |
isoenzyme PI-PLC-ß1 |
668867 |
3.1.4.11 | phosphoinositide phospholipase C |
HL-60 cell |
phosphorylation of nuclear PLC-beta1b on serine occurs at the G2/M and the late G1 phase and is necessary for the progression of the cells through the cell cycle |
667801 |
3.1.4.11 | phosphoinositide phospholipase C |
HL-60 cell |
promyelocytic cell line, undifferentiated and DMSO-differentiated |
650786 |
3.1.4.12 | sphingomyelin phosphodiesterase |
HL-60 cell |
- |
135176, 135180, 135187, 678375 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
HL-60 cell |
- |
682531 |
3.1.4.4 | phospholipase D |
HL-60 cell |
- |
664880, 708460 |
3.1.4.4 | phospholipase D |
HL-60 cell |
human leucemia cell line |
135440 |
3.1.4.4 | phospholipase D |
HL-60 cell |
the expression pattern of PLD1 and PLD2 mRNA isoforms induced to differentiate varies with DSMO and all-trans retinoic acid |
665957 |
3.1.4.4 | phospholipase D |
HL-60 cell |
the expression pattern of PLD1 and PLD2 mRNA isoforms induced to differentiate varies with DSMO and ATRA |
665957 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
HL-60 cell |
- |
711443 |
3.1.6.2 | steryl-sulfatase |
HL-60 cell |
acute myeloid leukaemia cell line |
665806 |
3.2.1.129 | endo-alpha-sialidase |
HL-60 cell |
- |
749567 |
3.2.1.143 | poly(ADP-ribose) glycohydrolase |
HL-60 cell |
promyelocytic leukemia cell line |
664169 |
3.2.1.18 | exo-alpha-sialidase |
HL-60 cell |
- |
700354 |
3.2.1.24 | alpha-mannosidase |
HL-60 cell |
human promyelocytic leukemia HL-60 cells |
681902 |
3.2.1.51 | alpha-L-fucosidase |
HL-60 cell |
- |
655418 |
3.2.1.53 | beta-N-acetylgalactosaminidase |
HL-60 cell |
- |
732374 |
3.2.2.5 | NAD+ glycohydrolase |
HL-60 cell |
leukemic cells, retinoic acid-treated |
654609 |
3.2.2.6 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase |
HL-60 cell |
- |
714921, 731296 |
3.2.2.6 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase |
HL-60 cell |
the enzymeis induced by retinoic acid, no activity in untreated cells |
731987 |
3.3.2.6 | leukotriene-A4 hydrolase |
HL-60 cell |
- |
753500 |
3.4.11.2 | membrane alanyl aminopeptidase |
HL-60 cell |
- |
698298 |
3.4.11.6 | aminopeptidase B |
HL-60 cell |
neutrophilic promyelocyte cell line |
666799 |
3.4.14.1 | dipeptidyl-peptidase I |
HL-60 cell |
- |
754144 |
3.4.17.1 | carboxypeptidase A |
HL-60 cell |
low expression level |
669629 |
3.4.19.9 | folate gamma-glutamyl hydrolase |
HL-60 cell |
- |
647319 |
3.4.21.108 | HtrA2 peptidase |
HL-60 cell |
- |
652027 |
3.4.21.37 | leukocyte elastase |
HL-60 cell |
- |
717895 |
3.4.21.76 | Myeloblastin |
HL-60 cell |
- |
29718, 710661 |
3.4.21.76 | Myeloblastin |
HL-60 cell |
cell associated PR3 levels are lower than in neutrophils, thus sensitivity of the indirect immunofluorescence test is lower |
686188 |
3.4.21.78 | granzyme A |
HL-60 cell |
no expression of granzyme A in promyelocytic cell line HL-60 identified |
683529 |
3.4.22.15 | cathepsin L |
HL-60 cell |
infection with Anaplasma phagocytophilum results in elevated cathepsin L activity and the proteolysis of CDP |
698246 |
3.4.22.40 | bleomycin hydrolase |
HL-60 cell |
- |
731954 |
3.4.22.49 | separase |
HL-60 cell |
- |
707105, 732703 |
3.4.22.53 | calpain-2 |
HL-60 cell |
calpain 2 localizes to GM-3-rich lipid rafts at the leading edge |
688909 |
3.4.22.56 | caspase-3 |
HL-60 cell |
- |
698767, 699113, 700544 |
3.4.22.56 | caspase-3 |
HL-60 cell |
promyelocytic cell |
647607 |
3.4.22.60 | caspase-7 |
HL-60 cell |
- |
699113 |
3.4.22.61 | caspase-8 |
HL-60 cell |
- |
710215, 753244 |
3.4.22.62 | caspase-9 |
HL-60 cell |
- |
700332 |
3.4.22.62 | caspase-9 |
HL-60 cell |
null mutant of protein p53 |
698357 |
3.4.22.62 | caspase-9 |
HL-60 cell |
undifferentiated and differentiated cells, differentiation induced by phorbol-12-myristate-13-acetate (TPA) |
697941 |
3.4.22.63 | caspase-10 |
HL-60 cell |
- |
754943 |
3.4.24.24 | gelatinase A |
HL-60 cell |
leukemia cell line, secretion of MMP-2 |
683579 |
3.4.24.35 | gelatinase B |
HL-60 cell |
leukemia cell line, secretion of MMP-9 |
683579 |
3.4.24.81 | ADAM10 endopeptidase |
HL-60 cell |
- |
720160, 755575 |
3.4.24.86 | ADAM 17 endopeptidase |
HL-60 cell |
- |
712600, 755575 |
3.4.24.B5 | matrix metalloproteinase-15 |
HL-60 cell |
- |
754240 |
3.4.24.B7 | matrix metalloproteinase-26 |
HL-60 cell |
promyelocytic leukemia, gene expression |
650768 |
3.4.25.1 | proteasome endopeptidase complex |
HL-60 cell |
- |
137358, 685565, 733663 |
3.5.1.23 | ceramidase |
HL-60 cell |
- |
752968 |
3.5.1.88 | peptide deformylase |
HL-60 cell |
- |
654445 |
3.5.1.98 | histone deacetylase |
HL-60 cell |
- |
712434 |
3.5.3.15 | protein-arginine deiminase |
HL-60 cell |
- |
664107, 733099 |
3.6.1.12 | dCTP diphosphatase |
HL-60 cell |
- |
757386 |
3.6.1.13 | ADP-ribose diphosphatase |
HL-60 cell |
- |
655991 |
3.6.1.29 | bis(5'-adenosyl)-triphosphatase |
HL-60 cell |
- |
719088 |
4.1.1.17 | ornithine decarboxylase |
HL-60 cell |
- |
677616, 699928, 699929, 699934 |
4.1.1.17 | ornithine decarboxylase |
HL-60 cell |
human acute myeloid leukemia cell, enzyme activity correlates with myeloid cell differentiation induced by retinoic acid treatment |
664295 |
4.4.1.20 | leukotriene-C4 synthase |
HL-60 cell |
monocytic leukemia cell line |
644492 |
4.4.1.5 | lactoylglutathione lyase |
HL-60 cell |
- |
691217 |
5.3.4.1 | protein disulfide-isomerase |
HL-60 cell |
- |
714600 |
5.3.99.5 | thromboxane-A synthase |
HL-60 cell |
low activity |
3183 |
5.6.1.3 | plus-end-directed kinesin ATPase |
HL-60 cell |
- |
670955 |
5.6.2.1 | DNA topoisomerase |
HL-60 cell |
- |
702564, 702602, 702620, 714463, 714900, 747693, 747698 |
5.6.2.1 | DNA topoisomerase |
HL-60 cell |
a myeloid leukemic tumor cell line |
714903 |
5.6.2.1 | DNA topoisomerase |
HL-60 cell |
promyelocytic leukemia cell line |
691221 |
5.6.2.2 | DNA topoisomerase (ATP-hydrolysing) |
HL-60 cell |
- |
3884, 678594, 681905, 691220, 691488, 691529, 693548, 695190, 702602, 702620, 714427, 714900, 715842, 716887, 727301, 750475 |
5.6.2.2 | DNA topoisomerase (ATP-hydrolysing) |
HL-60 cell |
a myeloid leukemic tumor cell line |
714903 |
5.6.2.2 | DNA topoisomerase (ATP-hydrolysing) |
HL-60 cell |
a promyelocytic leukemia cell line |
705067 |
5.6.2.2 | DNA topoisomerase (ATP-hydrolysing) |
HL-60 cell |
sensitive to topoisomerase II inhibitors |
678097 |
5.6.2.2 | DNA topoisomerase (ATP-hydrolysing) |
HL-60 cell |
vincristine-resistant leukemia cell line |
662920 |
6.1.1.20 | phenylalanine-tRNA ligase |
HL-60 cell |
promyelocytic leukemia cell line, high content |
649540 |
6.1.1.5 | isoleucine-tRNA ligase |
HL-60 cell |
- |
691288 |
6.3.2.17 | tetrahydrofolate synthase |
HL-60 cell |
- |
744775 |
6.3.4.2 | CTP synthase (glutamine hydrolysing) |
HL-60 cell |
- |
648969 |
6.3.4.21 | nicotinate phosphoribosyltransferase |
HL-60 cell |
- |
680797 |
7.4.2.14 | ABC-type antigen peptide transporter |
HL-60 cell |
- |
762296 |
7.6.2.1 | P-type phospholipid transporter |
HL-60 cell |
promyelocytic leukemia cells |
687676 |
7.6.2.2 | ABC-type xenobiotic transporter |
HL-60 cell |
- |
210395, 210399, 210400, 210401, 710872 |
7.6.2.2 | ABC-type xenobiotic transporter |
HL-60 cell |
MRP-overexpressing HL60/ADR cells |
210402 |