1.1.1.205 IMP dehydrogenase HL-60 cell leukemic cell line 347916 1.1.1.37 malate dehydrogenase HL-60 cell - 762064 1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase HL-60 cell - 671713 1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase HL-60 cell treatment with docosahexaenoic acid results in 60% decrease in GPx-4 level 688924 1.11.1.6 catalase HL-60 cell - 699926 1.11.1.9 glutathione peroxidase HL-60 cell - 688924 1.11.2.2 myeloperoxidase HL-60 cell - 697307, 713436, 742569, 764118, 765381 1.13.11.34 arachidonate 5-lipoxygenase HL-60 cell - 690170, 711301 1.13.11.34 arachidonate 5-lipoxygenase HL-60 cell the 5-lipoxygenase core promoter is unmethylated, expression of 5-lipoxygenase protein upon differentiation 704997 1.14.11.53 mRNA N6-methyladenine demethylase HL-60 cell - 763823 1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase HL-60 cell during the differentiation of leukemic HL60 cells, the decreased hTERT expression is accompanied by the LSD1 recruitment to the hTERT promoter 755188 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase HL-60 cell - 744722 1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase HL-60 cell - 753742 1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase HL-60 cell - 744722 1.14.11.B19 [histone H3]-trimethyl-L-lysine56 demethylase HL-60 cell low expression level 755194 1.14.14.94 leukotriene-B4 20-monooxygenase HL-60 cell induction of in all-trans-retinoic acid-treated HL60 cells 657762 1.14.14.94 leukotriene-B4 20-monooxygenase HL-60 cell promyelocytic leukemic cell line 703413 1.14.19.20 DELTA7-sterol 5(6)-desaturase HL-60 cell - 682873 1.14.99.38 cholesterol 25-monooxygenase HL-60 cell - 746440 1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase HL-60 cell during the differentiation of leukemic HL60 cells, the decreased hTERT expression is accompanied by the LSD1 recruitment to the hTERT promoter 755188 1.17.4.1 ribonucleoside-diphosphate reductase HL-60 cell - 744504, 744958 1.17.4.1 ribonucleoside-diphosphate reductase HL-60 cell a promyelocytic leukemia cell line 688283 1.17.4.1 ribonucleoside-diphosphate reductase HL-60 cell promyelocytic leukemia cell 726918 1.17.4.2 ribonucleoside-triphosphate reductase (thioredoxin) HL-60 cell - 687180 1.17.4.2 ribonucleoside-triphosphate reductase (thioredoxin) HL-60 cell promyelocytic leukemia cells 672890 1.3.1.21 7-dehydrocholesterol reductase HL-60 cell - 725672 1.3.1.72 DELTA24-sterol reductase HL-60 cell - 682873, 764619 1.3.1.72 DELTA24-sterol reductase HL-60 cell promyelocytic cells 654502 1.4.3.5 pyridoxal 5'-phosphate synthase HL-60 cell 2.3% of the activity in liver 655483 1.6.2.4 NADPH-hemoprotein reductase HL-60 cell - 743141, 743656 1.6.3.1 NAD(P)H oxidase (H2O2-forming) HL-60 cell - 685998, 711166, 763912 1.6.3.1 NAD(P)H oxidase (H2O2-forming) HL-60 cell bilirubin concentration-dependently reduces NADPH oxidase-dependent superoxide production stimulated by phorbol 12-myristate 13-acetate 687050 1.6.5.2 NAD(P)H dehydrogenase (quinone) HL-60 cell - 745830 1.7.1.7 GMP reductase HL-60 cell - 659550 1.8.1.7 glutathione-disulfide reductase HL-60 cell doxorubicin-insensitive leukemic cell line HL-60-R, a subclone of HL-60 657878 1.8.1.9 thioredoxin-disulfide reductase HL-60 cell - 688735 2.1.1.13 methionine synthase HL-60 cell - 684467, 733653 2.1.1.137 arsenite methyltransferase HL-60 cell - 718748, 733451 2.1.1.319 type I protein arginine methyltransferase HL-60 cell - 756861 2.1.1.355 [histone H3]-lysine9 N-trimethyltransferase HL-60 cell interaction between growth factor independent 1 and G9a in vivo 675958 2.1.1.6 catechol O-methyltransferase HL-60 cell - 657534 2.1.1.72 site-specific DNA-methyltransferase (adenine-specific) HL-60 cell - 719373 2.3.1.125 1-alkyl-2-acetylglycerol O-acyltransferase HL-60 cell - 486246 2.3.1.149 Platelet-activating factor acetyltransferase HL-60 cell - 16279 2.3.1.20 diacylglycerol O-acyltransferase HL-60 cell leukemia, HL-60 cell line 486246 2.3.1.67 1-alkylglycerophosphocholine O-acetyltransferase HL-60 cell differentiated 487375 2.3.1.85 fatty-acid synthase system HL-60 cell - 720118 2.4.1.143 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase HL-60 cell - 658123 2.4.1.144 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase HL-60 cell - 658123 2.4.1.150 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase HL-60 cell C2GnT, promyelocytic leukaemia HL-60 cells 638564 2.4.1.152 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase HL-60 cell - 639528 2.4.1.155 alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase HL-60 cell - 658123 2.4.1.206 lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase HL-60 cell - 704447 2.4.1.80 ceramide glucosyltransferase HL-60 cell - 489417, 691791 2.4.2.1 purine-nucleoside phosphorylase HL-60 cell - 703162 2.4.2.31 NAD+-protein-arginine ADP-ribosyltransferase HL-60 cell - 723565 2.4.2.8 hypoxanthine phosphoribosyltransferase HL-60 cell myeloid leukemic cell line 672965 2.4.3.8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase HL-60 cell - 764812 2.4.3.9 lactosylceramide alpha-2,3-sialyltransferase HL-60 cell - 657703 2.4.3.9 lactosylceramide alpha-2,3-sialyltransferase HL-60 cell phorbol myristate actetate-stimulated 658140 2.4.3.9 lactosylceramide alpha-2,3-sialyltransferase HL-60 cell the cAMP responsive element binding protein binding site of the hST3Gal V promoter plays a critical role in transcriptional regulation of the hST3Gal V gene during HL-60 cell differentiation 658723 2.4.3.9 lactosylceramide alpha-2,3-sialyltransferase HL-60 cell type 2 isozyme 672358 2.4.3.9 lactosylceramide alpha-2,3-sialyltransferase HL-60 cell upregulation of GM3 synthase through protein kinase C/extracellular regulated kinases-dependent cAMP-responsive element binding protein activation results in the differentiation of HL-60 cells by inducing expression of CD11b 658853 2.5.1.18 glutathione transferase HL-60 cell - 687298, 703157, 705056 2.5.1.39 4-hydroxybenzoate polyprenyltransferase HL-60 cell - 671299 2.5.1.49 O-acetylhomoserine aminocarboxypropyltransferase HL-60 cell - 684467 2.5.1.6 methionine adenosyltransferase HL-60 cell leukemia promyelotic cells 657534 2.7.1.107 diacylglycerol kinase (ATP) HL-60 cell level of DGKgamma is rapidly and markedly decreased upon cellular differentiation into macrophages 640373 2.7.1.107 diacylglycerol kinase (ATP) HL-60 cell levels of DGKgamma mRNA/protein is rapidly and markedly decreased upon cellular differentiation into macrophages 640373 2.7.1.113 deoxyguanosine kinase HL-60 cell - 671801 2.7.1.113 deoxyguanosine kinase HL-60 cell 3fold increase when cells start to proliferate 671801 2.7.1.127 inositol-trisphosphate 3-kinase HL-60 cell non-differentiated promyelocytic-leukaemia cell line, InsP3 3-kinase B mRNA 640751 2.7.1.138 ceramide kinase HL-60 cell - 691938 2.7.1.138 ceramide kinase HL-60 cell CerK mRNA expression and activity decreased during macrophagelike cell differentiation of HL-60 cells 692594 2.7.1.20 adenosine kinase HL-60 cell - 722914 2.7.1.60 N-acylmannosamine kinase HL-60 cell - 641741 2.7.1.68 1-phosphatidylinositol-4-phosphate 5-kinase HL-60 cell - 693300, 738199 2.7.1.68 1-phosphatidylinositol-4-phosphate 5-kinase HL-60 cell enzyme is enriched in the uropod during chemotaxis of differentiated HL-60 cells. Enrichment occurs early upon chemoattractant stimulation and is persistent during chemotaxis, concomitant with enrichment of phosphatidylinositol 4,5-bisphosphate 694079 2.7.1.74 deoxycytidine kinase HL-60 cell - 662521, 721969, 761020 2.7.1.91 sphingosine kinase HL-60 cell - 704087 2.7.10.2 non-specific protein-tyrosine kinase HL-60 cell macrophage-like differentiated 672781 2.7.10.2 non-specific protein-tyrosine kinase HL-60 cell promyelotic leukemia cell line 662838 2.7.11.1 non-specific serine/threonine protein kinase HL-60 cell - 723080 2.7.11.10 IkappaB kinase HL-60 cell - 722690, 722826 2.7.11.13 protein kinase C HL-60 cell - 491032 2.7.11.15 beta-adrenergic-receptor kinase HL-60 cell - 677232 2.7.11.15 beta-adrenergic-receptor kinase HL-60 cell high expression of beta-ARK 1 490989 2.7.11.17 Ca2+/calmodulin-dependent protein kinase HL-60 cell - 691612 2.7.11.30 receptor protein serine/threonine kinase HL-60 cell a myeloid leukemic cell line 691532 2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase HL-60 cell - 693328 2.7.12.2 mitogen-activated protein kinase kinase HL-60 cell - 679032, 740713 2.7.4.21 inositol-hexakisphosphate 5-kinase HL-60 cell - 662355 2.7.7.19 polynucleotide adenylyltransferase HL-60 cell - 761995 2.7.7.49 RNA-directed DNA polymerase HL-60 cell - 693312 2.7.7.96 ADP-D-ribose pyrophosphorylase HL-60 cell - 761999 2.7.8.27 sphingomyelin synthase HL-60 cell - 722907, 723525 3.1.1.47 1-alkyl-2-acetylglycerophosphocholine esterase HL-60 cell - 650326 3.1.1.77 acyloxyacyl hydrolase HL-60 cell - 246545, 246546, 246547, 246548, 246549, 246550 3.1.2.4 3-hydroxyisobutyryl-CoA hydrolase HL-60 cell promyelocytic leukemia cell line 665823 3.1.22.1 deoxyribonuclease II HL-60 cell - 696131 3.1.3.16 protein-serine/threonine phosphatase HL-60 cell - 692550 3.1.3.16 protein-serine/threonine phosphatase HL-60 cell a promyelocytic leukemia cell line 698767 3.1.3.25 inositol-phosphate phosphatase HL-60 cell - 114225 3.1.3.86 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase HL-60 cell - 714601 3.1.4.1 phosphodiesterase I HL-60 cell - 208356 3.1.4.11 phosphoinositide phospholipase C HL-60 cell - 678438, 679976, 682863 3.1.4.11 phosphoinositide phospholipase C HL-60 cell isoenzyme PI-PLC-ß1 668867 3.1.4.11 phosphoinositide phospholipase C HL-60 cell phosphorylation of nuclear PLC-beta1b on serine occurs at the G2/M and the late G1 phase and is necessary for the progression of the cells through the cell cycle 667801 3.1.4.11 phosphoinositide phospholipase C HL-60 cell promyelocytic cell line, undifferentiated and DMSO-differentiated 650786 3.1.4.12 sphingomyelin phosphodiesterase HL-60 cell - 135176, 135180, 135187, 678375 3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase HL-60 cell - 682531 3.1.4.4 phospholipase D HL-60 cell - 664880, 708460 3.1.4.4 phospholipase D HL-60 cell human leucemia cell line 135440 3.1.4.4 phospholipase D HL-60 cell the expression pattern of PLD1 and PLD2 mRNA isoforms induced to differentiate varies with DSMO and all-trans retinoic acid 665957 3.1.4.4 phospholipase D HL-60 cell the expression pattern of PLD1 and PLD2 mRNA isoforms induced to differentiate varies with DSMO and ATRA 665957 3.1.4.53 3',5'-cyclic-AMP phosphodiesterase HL-60 cell - 711443 3.1.6.2 steryl-sulfatase HL-60 cell acute myeloid leukaemia cell line 665806 3.2.1.129 endo-alpha-sialidase HL-60 cell - 749567 3.2.1.143 poly(ADP-ribose) glycohydrolase HL-60 cell promyelocytic leukemia cell line 664169 3.2.1.18 exo-alpha-sialidase HL-60 cell - 700354 3.2.1.24 alpha-mannosidase HL-60 cell human promyelocytic leukemia HL-60 cells 681902 3.2.1.51 alpha-L-fucosidase HL-60 cell - 655418 3.2.1.53 beta-N-acetylgalactosaminidase HL-60 cell - 732374 3.2.2.5 NAD+ glycohydrolase HL-60 cell leukemic cells, retinoic acid-treated 654609 3.2.2.6 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase HL-60 cell - 714921, 731296 3.2.2.6 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase HL-60 cell the enzymeis induced by retinoic acid, no activity in untreated cells 731987 3.3.2.6 leukotriene-A4 hydrolase HL-60 cell - 753500 3.4.11.2 membrane alanyl aminopeptidase HL-60 cell - 698298 3.4.11.6 aminopeptidase B HL-60 cell neutrophilic promyelocyte cell line 666799 3.4.14.1 dipeptidyl-peptidase I HL-60 cell - 754144 3.4.17.1 carboxypeptidase A HL-60 cell low expression level 669629 3.4.19.9 folate gamma-glutamyl hydrolase HL-60 cell - 647319 3.4.21.108 HtrA2 peptidase HL-60 cell - 652027 3.4.21.37 leukocyte elastase HL-60 cell - 717895 3.4.21.76 Myeloblastin HL-60 cell - 29718, 710661 3.4.21.76 Myeloblastin HL-60 cell cell associated PR3 levels are lower than in neutrophils, thus sensitivity of the indirect immunofluorescence test is lower 686188 3.4.21.78 granzyme A HL-60 cell no expression of granzyme A in promyelocytic cell line HL-60 identified 683529 3.4.22.15 cathepsin L HL-60 cell infection with Anaplasma phagocytophilum results in elevated cathepsin L activity and the proteolysis of CDP 698246 3.4.22.40 bleomycin hydrolase HL-60 cell - 731954 3.4.22.49 separase HL-60 cell - 707105, 732703 3.4.22.53 calpain-2 HL-60 cell calpain 2 localizes to GM-3-rich lipid rafts at the leading edge 688909 3.4.22.56 caspase-3 HL-60 cell - 698767, 699113, 700544 3.4.22.56 caspase-3 HL-60 cell promyelocytic cell 647607 3.4.22.60 caspase-7 HL-60 cell - 699113 3.4.22.61 caspase-8 HL-60 cell - 710215, 753244 3.4.22.62 caspase-9 HL-60 cell - 700332 3.4.22.62 caspase-9 HL-60 cell null mutant of protein p53 698357 3.4.22.62 caspase-9 HL-60 cell undifferentiated and differentiated cells, differentiation induced by phorbol-12-myristate-13-acetate (TPA) 697941 3.4.22.63 caspase-10 HL-60 cell - 754943 3.4.24.24 gelatinase A HL-60 cell leukemia cell line, secretion of MMP-2 683579 3.4.24.35 gelatinase B HL-60 cell leukemia cell line, secretion of MMP-9 683579 3.4.24.81 ADAM10 endopeptidase HL-60 cell - 720160, 755575 3.4.24.86 ADAM 17 endopeptidase HL-60 cell - 712600, 755575 3.4.24.B5 matrix metalloproteinase-15 HL-60 cell - 754240 3.4.24.B7 matrix metalloproteinase-26 HL-60 cell promyelocytic leukemia, gene expression 650768 3.4.25.1 proteasome endopeptidase complex HL-60 cell - 137358, 685565, 733663 3.5.1.23 ceramidase HL-60 cell - 752968 3.5.1.88 peptide deformylase HL-60 cell - 654445 3.5.1.98 histone deacetylase HL-60 cell - 712434 3.5.3.15 protein-arginine deiminase HL-60 cell - 664107, 733099 3.6.1.12 dCTP diphosphatase HL-60 cell - 757386 3.6.1.13 ADP-ribose diphosphatase HL-60 cell - 655991 3.6.1.29 bis(5'-adenosyl)-triphosphatase HL-60 cell - 719088 4.1.1.17 ornithine decarboxylase HL-60 cell - 677616, 699928, 699929, 699934 4.1.1.17 ornithine decarboxylase HL-60 cell human acute myeloid leukemia cell, enzyme activity correlates with myeloid cell differentiation induced by retinoic acid treatment 664295 4.4.1.20 leukotriene-C4 synthase HL-60 cell monocytic leukemia cell line 644492 4.4.1.5 lactoylglutathione lyase HL-60 cell - 691217 5.3.4.1 protein disulfide-isomerase HL-60 cell - 714600 5.3.99.5 thromboxane-A synthase HL-60 cell low activity 3183 5.6.1.3 plus-end-directed kinesin ATPase HL-60 cell - 670955 5.6.2.1 DNA topoisomerase HL-60 cell - 702564, 702602, 702620, 714463, 714900, 747693, 747698 5.6.2.1 DNA topoisomerase HL-60 cell a myeloid leukemic tumor cell line 714903 5.6.2.1 DNA topoisomerase HL-60 cell promyelocytic leukemia cell line 691221 5.6.2.2 DNA topoisomerase (ATP-hydrolysing) HL-60 cell - 3884, 678594, 681905, 691220, 691488, 691529, 693548, 695190, 702602, 702620, 714427, 714900, 715842, 716887, 727301, 750475 5.6.2.2 DNA topoisomerase (ATP-hydrolysing) HL-60 cell a myeloid leukemic tumor cell line 714903 5.6.2.2 DNA topoisomerase (ATP-hydrolysing) HL-60 cell a promyelocytic leukemia cell line 705067 5.6.2.2 DNA topoisomerase (ATP-hydrolysing) HL-60 cell sensitive to topoisomerase II inhibitors 678097 5.6.2.2 DNA topoisomerase (ATP-hydrolysing) HL-60 cell vincristine-resistant leukemia cell line 662920 6.1.1.20 phenylalanine-tRNA ligase HL-60 cell promyelocytic leukemia cell line, high content 649540 6.1.1.5 isoleucine-tRNA ligase HL-60 cell - 691288 6.3.2.17 tetrahydrofolate synthase HL-60 cell - 744775 6.3.4.2 CTP synthase (glutamine hydrolysing) HL-60 cell - 648969 6.3.4.21 nicotinate phosphoribosyltransferase HL-60 cell - 680797 7.4.2.14 ABC-type antigen peptide transporter HL-60 cell - 762296 7.6.2.1 P-type phospholipid transporter HL-60 cell promyelocytic leukemia cells 687676 7.6.2.2 ABC-type xenobiotic transporter HL-60 cell - 210395, 210399, 210400, 210401, 710872 7.6.2.2 ABC-type xenobiotic transporter HL-60 cell MRP-overexpressing HL60/ADR cells 210402