EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
|---|
    1.8.1.12 | 764502 |
Biological evaluation and X-ray co-crystal structures of cyclohexylpyrrolidine ligands for trypanothione reductase, an enzyme from the redox metabolism of Trypanosoma |
ChemMedChem |
13 |
957-967 |
2018 |
Trypanosoma cruzi |
29624890 |
| 1.8.1.12 | 764502 |
Biological evaluation and X-ray co-crystal structures of cyclohexylpyrrolidine ligands for trypanothione reductase, an enzyme from the redox metabolism of Trypanosoma |
ChemMedChem |
13 |
957-967 |
2018 |
Trypanosoma brucei brucei |
29624890 |
| 1.8.1.12 | 764502 |
Biological evaluation and X-ray co-crystal structures of cyclohexylpyrrolidine ligands for trypanothione reductase, an enzyme from the redox metabolism of Trypanosoma |
ChemMedChem |
13 |
957-967 |
2018 |
Trypanosoma brucei brucei 927/4 GUTat10.1 |
29624890 |
| 1.8.1.12 | 742920 |
Developing imidazole analogues as potential inhibitor for Leishmania donovani trypanothione reductase virtual screening, molecular docking, dynamics and ADMET approach |
J. Biomol. Struct. Dyn. |
33 |
2541-2553 |
2015 |
Leishmania donovani |
26305585 |
| 1.8.1.12 | 742922 |
Febrifugine analogues as Leishmania donovani trypanothione reductase inhibitors binding energy analysis assisted by molecular docking, ADMET and molecular dynamics simulation |
J. Biomol. Struct. Dyn. |
35 |
141-158 |
2017 |
Leishmania donovani |
27043972 |
| 1.8.1.12 | 764697 |
Glucose-6-phosphate dehydrogenase and trypanothione reductase interaction protects Leishmania donovani from metalloid mediated oxidative stress |
Free Radic. Biol. Med. |
106 |
10-23 |
2017 |
Leishmania donovani |
28179112 |
| 1.8.1.12 | 765431 |
Identification of 3-methoxycarpachromene and masticadienonic acid as new target inhibitors against trypanothione reductase from Leishmania infantum using molecular docking and ADMET prediction |
Molecules |
26 |
3335 |
2021 |
Leishmania infantum |
34206087 |
| 1.8.1.12 | 765838 |
Identification of novel thiadiazin derivatives as potentially selective inhibitors towards trypanothione reductase from Trypanosoma cruzi by molecular docking using the numerical index poses ratio Pr and the binding mode analysis |
SN Appl. Sci. |
3 |
376 |
2021 |
Trypanosoma cruzi |
- |
| 1.8.1.12 | 765386 |
Identification of potential trypanothione reductase inhibitors among commercially available beta-carboline derivatives using chemical space, lead-like and drug-like filters, pharmacophore models and molecular docking |
Mol. Divers. |
21 |
697-711 |
2017 |
Trypanosoma cruzi |
28656524 |
| 1.8.1.12 | 742987 |
Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives |
J. Enzyme Inhib. Med. Chem. |
32 |
304-310 |
2017 |
Leishmania infantum |
28098499 |
