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EC Number
Natural Substrates
Commentary (Nat. Sub.)
1.1.1.1
1-butanol + NAD+
-
1.1.1.1
2-dehydro-3-deoxy-D-gluconate + NADH + H+
-
1.1.1.1
4-deoxy-L-erythro-5-hexoseulose + NAD+
preferred reaction
1.1.1.1
a primary alcohol + NAD+
ADH3 is involved in multiple cellular pathways, as diverse as formaldehyde detoxification, retinoid metabolism and NO homeostasis, ADH3 is considered to play only a minor role in hepatic alcohol metabolism because ethanol concentrations rarely exceed 50 mM
1.1.1.1
acetaldehyde + NADH + H+
-
1.1.1.1
acetaldehyde + NADH + H+
cells with an extra copy of ADH1 display chronological life-span extension. Antioxidant enzymes are induced in 2xADH1 cells. Strains carrying an extra ADH1 copy show extended replicative life span and increased Sir2p activity
1.1.1.1
all-trans-retinol + NAD+
-
1.1.1.1
all-trans-retinol + NAD+
ADH4 might be involved in biosynthesis of retinoic acid
1.1.1.1
allyl alcohol + NAD+
-
1.1.1.1
cinnamaldehyde + NADH + H+
-
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