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Disease on EC 1.14.19.28 - sn-1 stearoyl-lipid 9-desaturase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Carcinogenesis
DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by down-regulating the EGFR/AKT pathway in esophageal squamous cell carcinoma.
Carcinoma
Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family.
DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by down-regulating the EGFR/AKT pathway in esophageal squamous cell carcinoma.
Differential expression of a novel serine protease homologue in squamous cell carcinoma of the head and neck.
Expression of the serine protease DESC1 correlates directly with normal keratinocyte differentiation and inversely with head and neck squamous cell carcinoma progression.
Human DESC1 serine protease confers tumorigenic properties to MDCK cells and it is upregulated in tumours of different origin.
LncRNA LOXL1-AS1 promotes esophageal squamous cell carcinoma progression by targeting DESC1.
LncRNA-TUSC7/miR-224 affected chemotherapy resistance of esophageal squamous cell carcinoma by competitively regulating DESC1.
Carcinoma, Squamous Cell
Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family.
Differential expression of a novel serine protease homologue in squamous cell carcinoma of the head and neck.
Expression of the serine protease DESC1 correlates directly with normal keratinocyte differentiation and inversely with head and neck squamous cell carcinoma progression.
Human DESC1 serine protease confers tumorigenic properties to MDCK cells and it is upregulated in tumours of different origin.
Coronavirus Infections
DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.
Esophageal Squamous Cell Carcinoma
DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by down-regulating the EGFR/AKT pathway in esophageal squamous cell carcinoma.
LncRNA LOXL1-AS1 promotes esophageal squamous cell carcinoma progression by targeting DESC1.
LncRNA-TUSC7/miR-224 affected chemotherapy resistance of esophageal squamous cell carcinoma by competitively regulating DESC1.
Influenza, Human
DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.
Neoplasms
Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family.
DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by down-regulating the EGFR/AKT pathway in esophageal squamous cell carcinoma.
Human DESC1 serine protease confers tumorigenic properties to MDCK cells and it is upregulated in tumours of different origin.
Severe Acute Respiratory Syndrome
DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.
Squamous Cell Carcinoma of Head and Neck
Expression of the serine protease DESC1 correlates directly with normal keratinocyte differentiation and inversely with head and neck squamous cell carcinoma progression.