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2.7.1.30: glycerol kinase

This is an abbreviated version!
For detailed information about glycerol kinase, go to the full flat file.

Word Map on EC 2.7.1.30

Reaction

ATP
+
glycerol
=
ADP
 +
sn-glycerol 3-phosphate

Synonyms

AFUB_068560, ASTP , ATP-stimulated glucocorticoid-receptor translocation promoter , ATP: glycerol 3-phosphotransferase, ATP: glycerol-3-phosphotransferase, ATP:glycerol 3-phosphotransferase, ATP:glycerol 3-phosphotransferase , ATP:glycerol-3-phosphotransferase, GK, GK1, GK2, GK3, GK4, GK5, glcA, GLPK, glyceric kinase, glycerokinase, glycerol kinase, glycerol kinase 2, glycerol kinase 5, GLYK, GUT1, GYK, kinase, glycerol (phosphorylating), KpGlpK, More, slr1672, TbgGK, Tk-GK

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.30 glycerol kinase

Expression

Expression on EC 2.7.1.30 - glycerol kinase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
in ambient smelt, activity remains constant until April when it starts to increase significantly to reach a maximum in May at levels almost 25times higher than those recorded in November
-
isoform GK1 expression is significantly enhanced by exposure to 4°C
-
phenol treatment increases the glycerol kinase activity in the overexpressing strains whereas increasing concentrations of phenol decrease the glycerol kinase activity in the wild-type strain
RT-PCR analysis reveals that the expression of glpK is upregulated from 1.3 to 2.4 and from 1.89 to 3.64fold after phenol treatment and glycerol supplementation, respectively, overview. Phenol treatment increases the glycerol kinase activity in the overexpressing strains whereas increasing concentrations of phenol decrease the glycerol kinase activity in the wild-type strain
the mRNA and protein levels of GK5 are significantly upregulated in gefitinib-resistant human lung adenocarcinoma PC9R and H1975 cells compared with gefitinib-sensitive PC9 cells
transcript is upregulated by addition of glycerol
-
upregulated in diapause eggs exposed to 5°C
upregulated in sexual blood stage parasite