2.7.1.22: ribosylnicotinamide kinase

This is an abbreviated version!
For detailed information about ribosylnicotinamide kinase, go to the full flat file.

Reaction

Synonyms

kinase, ribosylnicotinamide (phosphorylating), More, muscle-specific beta1 integrin binding protein, NadR, nicotinamide ribose kinase, nicotinamide riboside kinase, nicotinamide riboside kinase 1, nicotinamide riboside kinase 2, nicotinamide riboside kinase-2, NmR-K, NMRK1, NMRK2, NR kinase 1, Nrk, NRK-2, NRK1, Nrk2, Nrk2b

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.22 ribosylnicotinamide kinase

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Results	in table
1041	AA Sequence
1	Application
1	CAS Registry Number
12	Cloned(Commentary)
8	Cofactor
2	Crystallization (Commentary)
17	Disease/ Diagnostics
9	Expression
35	General Information
1	Inhibitors
4	kcat/KM [mM/s]
9	KM Value [mM]
2	Localization
6	Metals/Ions
3	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
24	Organism
5	Pathway
2	PDB ID
2	pH Optimum
1	pH Range
11	Protein Variants
7	Purification (Commentary)
5	Reaction
1	Reaction Type
21	Reference
31	Source Tissue
7	Specific Activity [micromol/min/mg]
1	Storage Stability
29	Substrates and Products (Substrate)
1	Subunits
55	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
5	Turnover Number [1/s]

Disease

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Disease on EC 2.7.1.22 - ribosylnicotinamide kinase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Cardiomyopathy, Dilated

NMRK2 Gene Is Upregulated in Dilated Cardiomyopathy and Required for Cardiac Function and NAD Levels during Aging.

33805532

Glucose Intolerance

Tissue-specific regulation of sirtuin and nicotinamide adenine dinucleotide biosynthetic pathways identified in C57Bl/6 mice in response to high-fat feeding.

27592202

Heart Diseases

Nicotinamide riboside kinase-2 alleviates ischemia-induced heart failure through P38 signaling.

31743747

Heart Failure

Nicotinamide riboside kinase-2 alleviates ischemia-induced heart failure through P38 signaling.

31743747

ribosylnicotinamide kinase deficiency

Nicotinamide riboside kinase-2 alleviates ischemia-induced heart failure through P38 signaling.

31743747

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