2.3.2.B12: ubiquitin transferase U-box E4

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For detailed information about ubiquitin transferase U-box E4, go to the full flat file.

Reaction

Synonyms

CHIP, CYC4, DUF1076 domain-containing protein, E4, E4 factor, E4 ligase, E4 ubiquitin ligase, E4 ubiquitin-protein ligase UFD2, MUSE3, PRP19, StoD, STY1076, Ub-conjugating E4 factor, Ube4A, UBE4B, ubiquitin chain elongation enzyme Ufd2, ubiquitin conjugation factor E4, ubiquitin fusion degradation protein 2, Ubr1-dependent E4 enzyme, UFD-2, Ufd2, Ufd2a, Ufd2b, Ufd4, Ufd4-enhancing ubiquitiylation enzyme

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.2 Aminoacyltransferases

                2.3.2.B12 ubiquitin transferase U-box E4

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Results	in table
7	AA Sequence
2	Application
4	Cloned(Commentary)
2	Crystallization (Commentary)
3	Disease/ Diagnostics
9	General Information
5	Localization
2	Natural Substrates/ Products (Substrates)
19	Organism
5	Protein Variants
1	Purification (Commentary)
3	Reaction
18	Reference
12	Source Tissue
20	Substrates and Products (Substrate)
35	Synonyms
1	Systematic Name

Disease

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Disease on EC 2.3.2.B12 - ubiquitin transferase U-box E4

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Neuroblastoma

UFD2a mediates the proteasomal turnover of p73 without promoting p73 ubiquitination.

16170377

Neurodegenerative Diseases

Mammalian E4 is required for cardiac development and maintenance of the nervous system.

16314518

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