2.3.1.66: leucine N-acetyltransferase

This is an abbreviated version!
For detailed information about leucine N-acetyltransferase, go to the full flat file.

Reaction

Synonyms

acetyltransferase, leucine, leucine acyltransferase

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.66 leucine N-acetyltransferase

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Results	in table
1	CAS Registry Number
4	Inhibitors
2	KM Value [mM]
2	Metals/Ions
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
1	Organism
1	pH Optimum
1	pH Range
1	Purification (Commentary)
1	Reaction
1	Reaction Type
1	Reference
1	Storage Stability
7	Substrates and Products (Substrate)
2	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Substrates Products

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Substrates Products on EC 2.3.1.66 - leucine N-acetyltransferase

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acetyl-CoA + L-arginine

CoA + ?

Streptomyces roseus

487374

acetyl-CoA + L-leucine

CoA + N-acetyl-L-leucine

Streptomyces roseus

487374

acetyl-CoA + L-phenylalanine

CoA + N-acetyl-L-phenylalanine

Streptomyces roseus

487374

acetyl-CoA + L-valine

CoA + N-acetyl-L-valine

Streptomyces roseus

487374

propionyl-CoA + L-leucine

CoA + propionyl-L-leucine

Streptomyces roseus

10% of activity compared to acetyl-CoA

487374

additional information

Streptomyces roseus

dipeptides, e.g. L-leucyl-L-leucine, are acetylated more rapidly than L-leucine or peptides with more than two amino acids, D-isomers are acetylated more slowly than L-isomers

487374