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2.1.1.268: tRNAThr (cytosine32-N3)-methyltransferase

This is an abbreviated version!
For detailed information about tRNAThr (cytosine32-N3)-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.268

Reaction

S-adenosyl-L-methionine
+
cytosine32 in tRNASer
=
S-adenosyl-L-homocysteine
+
N3-methylcytosine32 in tRNASer

Synonyms

ABP140, METTL2B, Trm140

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.268 tRNAThr (cytosine32-N3)-methyltransferase

Natural Substrates Products

Natural Substrates Products on EC 2.1.1.268 - tRNAThr (cytosine32-N3)-methyltransferase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + cytosine32 in tRNA1Ser
S-adenosyl-L-homocysteine + N3-methylcytosine32 in tRNA1Ser
show the reaction diagram
tRNASer1 = tRNASer(UGA). Because position 32 of tRNA has an important role in accurate codon recognition, N3-methylcytosine32 formation in tRNAThr1 or tRNASer1 might play a role in modulating codon recognition and translational efficiency
-
-
?
S-adenosyl-L-methionine + cytosine32 in tRNA1Thr
S-adenosyl-L-homocysteine + N3-methylcytosine32 in tRNA1Thr
show the reaction diagram
tRNAThr1 = tRNAThr(IGU). Because position 32 of tRNA has an important role in accurate codon recognition, N3-methylcytosine32 formation in tRNAThr1 or tRNASer1 might play a role in modulating codon recognition and translational efficiency
-
-
?
S-adenosyl-L-methionine + cytosine32 in tRNASer
S-adenosyl-L-homocysteine + N3-methylcytosine32 in tRNASer
show the reaction diagram
S-adenosyl-L-methionine + cytosine32 in tRNAThr
S-adenosyl-L-homocysteine + N3-methylcytosine32 in tRNAThr
show the reaction diagram
additional information
?
-